Dr. Hale [HHMI Fellow] is focusing on the basic biological processes that allow cells to coordinate the replication of their genes with the regulation of when those genes are turned on/off.  By studying the interplay of these two biological processes, he hopes to elucidate how tumor cells are able to bypass the strict controls that a cell uses to normally operate each process.

 

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Project Title: "Understanding how a histone methyltransferase links DNA replication, repair and transcription"

Institution: University of California, Los Angeles

Sponsor(s) / Mentor(s): Steven E. Jacobsen, PhD

Cancer Type: All cancers

Research Area: Genomics