Dr. Kim is studying how noncoding RNAs (unique RNAs that do not make proteins) control gene expression during a developmental process in females called X-inactivation, which turns off all genes on an entire chromosome.  His work may provide insights into novel regulatory roles for noncoding RNAs in silencing tumor suppressor genes, while potentially revealing new therapeutic targets for the treatment of many types of cancer.

 

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Project Title: "Epigenetic regulation of X-chromosome inactivation by noncoding RNAs"

Institution: California Institute of Technology

Sponsor(s) / Mentor(s): Barbara J. Wold, PhD

Cancer Type: All cancers

Research Area: Chromatin Biology