Dr. Osborne [HHMI Fellow] is examining asymmetric cell division, a process that when disrupted has been linked to cancer occurrence and progression. By combining deep sequencing technology with single-cell dissection, she hopes to fully characterize unequal RNA transcript partitioning that occurs during asymmetric cell division and to identify cellular components important for cancer occurrence, prevention and therapy.

 

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Project Title: "When paths diverge: patterns and mechanisms of asymmetric cell division"

Institution: University of North Carolina, Chapel Hill

Sponsor(s) / Mentor(s): Jason D. Lieb, PhD

Cancer Type: All cancers

Research Area: Genomics