Dr. Sims is using biochemistry and mathematical modeling to study the molecular mechanisms by which cells commit to programmed cell death. Tumor cells acquire changes that allow them to evade this fate, a property that is critical for disease progression and often underlies resistance to treatment.

 

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Project Title: "Regulation of mitochondrial apoptosis"

Institution: Harvard Medical School

Sponsor(s) / Mentor(s): Peter K. Sorger, PhD

Cancer Type: All cancers

Research Area: Cell Death