Dr. Calabrese [HHMI Fellow] is studying how cell division is regulated, in part, by the attachment of a protein called ubiquitin to other proteins throughout the cell.  Understanding how ubiqutin is attached to its targets and how this attachment is recognized by cellular machinery is critical to understanding normal cell division as well as unregulated cell division associated with cancer.

 

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Project Title: "Ubiquitin interactions with a novel ubiquitin recognition motif"

Institution: St. Jude Children's Research Hospital

Sponsor(s) / Mentor(s): Brenda A. Schulman, PhD

Cancer Type: Breast, Colorectal, Gynecological

Research Area: Structural Biology