Dr. Bradshaw is studying the regulation of an enzyme called protein phosphatase that acts in specific cells to promote cellular differentiation.  Protein phosphatases are required for many processes, including cell growth, division, differentiation and stress adaptation.  He hopes that understanding phosphatase regulation will clarify the role of these enzymes in cancer and potentially aid in the development of anti-cancer therapies that target phosphatases.

 

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Project Title: "Regulation of the SpoIIE phosphatase and activation of a cell-specific transcription factor"

Institution: Harvard University

Sponsor(s) / Mentor(s): Richard M. Losick, PhD

Cancer Type: All cancers

Research Area: Cell Biology