Dr. Joshi is studying the response of the body’s immune system to tumors.  The goal of his research is to understand how cells of the immune system interact with growing tumors and why these cells are not able to effectively kill tumors.  One particular type of immune cell, the regulatory T cell, blocks anti-tumor immune cells from killing tumor cells.  Understanding how regulatory T cells function and how they promote tumor growth may be critical to developing future immune-based treatments and therapies for cancer patients. 

 

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Project Title: "Understanding the development and function of regulatory T cells in an autochthonous mouse model of human non-small cell lung cancer"

Institution: Massachusetts Institute of Technology

Sponsor(s) / Mentor(s): Tyler Jacks, PhD

Cancer Type: Lung

Research Area: Tumor Immunology