Dr. Batista [Kenneth G. and Elaine A. Langone Fellow] is investigating the molecular mechanism by which long noncoding RNAs regulate gene expression. Long noncoding RNAs form a vital link between the information encoded in the genome and the instructions recorded at the structural chromatin level, thus maintaining cell identity. Understanding how long noncoding RNAs regulate gene expression will allow the development of powerful tools for diagnosis and treatment of cancer.

 

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Project Title: "LincRNA dependent transcriptional memory in cancer stem cells"

Institution: Stanford University School of Medicine

Sponsor(s) / Mentor(s): Howard Y. Chang, MD, PhD

Cancer Type: Breast, Leukemias

Research Area: Epigenetics