Dr. Montgomery is studying mechanisms of gene silencing by a class of small regulatory molecules called microRNAs.  In addition to having essential roles in development, microRNAs can act as oncogenes or as tumor suppressors.  MicroRNAs have tremendous potential to be used therapeutically to prevent and treat cancer.

 

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Project Title: "Mechanisms of microRNA-directed RNA silencing"

Institution: Massachusetts General Hospital

Sponsor(s) / Mentor(s): Gary Ruvkun, PhD

Cancer Type: All cancers

Research Area: RNA