Dr. Hartl [Robert Black Fellow] is studying the Hedgehog (Hh) signaling pathway, which is required for the proper growth, patterning and function of specialized cellular tissues. When the Hh pathway goes awry, increased cell growth signals can lead to tumorigenesis. Previous work has demonstrated that a specific lipid molecule can induce the Hh pathway to go awry. His research focuses on how this lipid alters the Hh pathway; he hopes that his findings will lead to better methods of cancer treatment.

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Project Title: "The role of lipids in Hedgehog signal transduction"

Institution: Stanford University School of Medicine

Sponsor(s) / Mentor(s): Matthew P. Scott, PhD

Cancer Type: All cancers

Research Area: Neuroscience