2009 Recipients (Three-year Awards)

Andrew L. Feldman, MD
"Investigation of IRF4 as a therapeutic target in T-cell lymphomas" with Stephen M. Ansell, MD, PhD, and Ahmet Dogan, MD, PhD, at the Mayo Clinic, Rochester, Minnesota

William Y. Kim, MD
Damon Runyon-Merck Clinical Investigator
"Molecular determinants of clinical response to EGFR inhibition in bladder cancer" with Charles M. Perou, PhD, at the University of North Carolina, Chapel Hill, North Carolina

C. Ryan Miller, MD, PhD
Damon Runyon-Genentech Clinical Investigator
"Genomics-driven drug development for glioblastoma" with Charles M. Perou, PhD, and Terry Van Dyke, PhD, at the University of North Carolina, Chapel Hill, North Carolina

Vu H. Nguyen, MD
August M. Watanabe, MD, Investigator of the Damon Runyon Foundation
"Organ-specific regulatory T cells as a targeted therapy for graft-versus-host disease" with Thomas F. Gajewski, MD, PhD, The University of Chicago, Chicago, Illinois

2008 Recipients (Three-year Awards)

Ronald J. Buckanovich, MD, PhD
"Tumor endothelial cells as a therapeutic and diagnostic target in ovarian cancer" with Daniel F. Hayes, MD, and Max S. Wicha, MD, University of Michigan, Ann Arbor, Michigan

Andrew T. Chan, MD, MPH
"Molecular imaging of colorectal neoplasia" with Charles S. Fuchs, MD, MPH, and Ralph Weissleder, MD, PhD, Massachusetts General Hospital, Boston, Massachusetts

Rachael A. Clark, MD, PhD
"Reversing immune evasion in human squamous cell carcinomas of the skin" with Thomas S. Kupper, MD, Brigham and Women's Hospital, Boston, Massachusetts

Vassiliki Karantza-Wadsworth, MD, PhD
"Autophagy as a therapeutic target in breast cancer treatment" with Robert S. DiPaola, MD, UMDNJ/Robert Wood Johnson Medical School, New Brunswick, New Jersey

Elahe A. Mostaghel, MD, PhD
Damon Runyon-Genentech Clinical Investigator
"Defining and exploiting molecular mechanisms of androgen-metabolism for prostate cancer therapy" with Peter S. Nelson, MD, Fred Hutchinson Cancer Research Center, Seattle, Washington

2007 Recipients (Three-year Awards)

Colleen Delaney, MD, MSc
Damon Runyon-Novartis Clinical Investigator
“Notch-mediated ex vivo expansion of cord blood progenitors for hematopoietic cell transplantation” with Irwin D. Bernstein, MD, and Frederick R. Appelbaum, MD, Fred Hutchinson Cancer Research Center, Seattle, Washington

Douglas K. Graham, MD, PhD
Damon Runyon-Novartis Clinical Investigator
“Novel biologically targeted therapy against the Mer receptor tyrosine kinase in the treatment of pediatric ALL” with James V. DeGregori, PhD, and Sue Gail Eckhardt, MD, University of Colorado Denver, Aurora, Colorado

Juan Carlos Ramos, MD
Damon Runyon-Genentech Clinical Investigator
“Resistance to interferon-based therapy in adult T-cell leukemia” with William J. Harrington, MD, and Glen N. Barber, PhD, University of Miami School of Medicine, Miami, Florida

Joel H. Rubenstein, MD
Gordon Family Clinical Investigator
“The epidemiology of adipokines in Barrett's esophagus” with John M. Inadomi, MD, and Philip S. Schoenfeld, MD, University of Michigan Medical School, Ann Arbor, Michigan

Catherine J. Wu, MD
“Immune-targeted leukemia antigens for eradication of CML stem cells” with Jerome Ritz, MD, Dana-Farber Cancer Institute, Boston, Massachusetts

2006 Recipients (Three-year Awards)

♦ Renier J. Brentjens, MD, PhD
Damon Runyon-Lilly Clinical Investigator
“Adoptive therapy of B cell leukemias with genetically modified autologous T cells” with Michel Sadelain, MD, PhD, Memorial Sloan Kettering Cancer Center, New York, New York

♦ Patrick A. Brown, MD
Damon Runyon-Lilly Clinical Investigator
“Translating FLT3 inhibition into improved outcome for high risk childhood leukemia” with Donald Small, MD, PhD, The Johns Hopkins University, Baltimore, Maryland

Delphine L. Chen, MD
Damon Runyon-Siemens Clinical Investigator
“Apoptosis imaging” with Michael J. Welch, PhD, Washington University School of Medicine, St. Louis, Missouri

♦ Andrea L. Cox, MD, PhD
“Analysis and manipulation of cross reactive immune responses to partial escape mutations in chronic Hepatitis C virus infection” with Drew M. Pardoll, MD, PhD, The Johns Hopkins University, Baltimore, Maryland

Loren S. Michel, MD
Damon Runyon-Lilly Clinical Investigator
“Characterization of the Trop-2 receptor in breast cancer progression” with Matthew J. Ellis, MB, PhD, Washington University School of Medicine, St. Louis, Missouri

♦ These investigators have been awarded two-year Continuation Grants.

2005 Recipients (Five-year Awards)

Marcia S. Brose, MD, PhD
Damon Runyon-Siemens Clinical Investigator
"The emerging clinical role of genetics in the treatment and diagnosis of thyroid cancer" with Susan J. Mandel, MD, MPH and Peter J. O'Dwyer, MD, University of Pennsylvania, Philadelphia, Pennsylvania

Christine H. Chung, MD
Damon Runyon-Lilly Clinical Investigator
"Gene expression-based outcome prediction in head and neck cancer" with David P. Carbone, MD, PhD, Vanderbilt University Medical Center, Nashville, Tennessee

Phillip G. Febbo, MD
Damon Runyon-Lilly Clinical Investigator
"Mechanisms of docetaxel resistance in metastatic prostate cancer" with H. Kim Lyerly, MD and Joseph Nevins, PhD, Duke University Medical Center, Durham, North Carolina

John M. Pagel, MD, PhD
Damon Runyon-Lilly Clinical Investigator
"Radioimmunotherapy of CD45+ leukemias" with Oliver W. Press, MD, PhD, Fred Hutchinson Cancer Research Center, Seattle, Washington

John M. Timmerman, MD
Damon Runyon-Lilly Clinical Investigator
"Dendritic cell-based outcome prediction in head and neck cancer" with Steven M. Dubinett, MD and Charles L. Sawyers, MD, University of California, Los Angeles, California

2004 Recipients (Five-year Awards)

Charles G. Drake, MD, PhD
Damon Runyon-Lilly Clinical Investigator
"Integrating clinical and laboratory studies to develop immunotherapy for prostate cancer" with Drew M. Pardoll, MD, PhD, The Johns Hopkins University, Baltimore, Maryland

Jakob Dupont, MD
Damon Runyon-Lilly Clinical Investigator
"Development and analysis of tumor-specific T cells for adoptive immunotherapy of epithelial ovarian cancer" with Richard J. O'Reilly, MD, Memorial Sloan-Kettering Cancer Center, New York, New York

John V. Heymach, MD, PhD
Damon Runyon-Lilly Clinical Investigator
"VEGF receptor inhibitors for non-small cell lung cancer: clinical studies and novel surrogate markers of activity" with Isaiah J. Fidler, DVM, PhD and Waun Ki Hong, MD, MD Anderson Cancer Center, Houston, Texas

Jeremy N. Rich, MD
Damon Runyon-Lilly Clinical Investigator
"Maximizing clinical efficacy of epidermal growth factor receptor tyrosine kinase inhibitors in glioblastoma therapy" with Henry S. Friedman, MD and Darrell Bigner, MD, PhD, Cleveland Clinic Foundation, Cleveland, Ohio

2003 Recipients (Five-Year Awards)

Scott A. Armstrong, MD, PhD
Damon Runyon-Lilly Clinical Investigator
“Genomic identification of new therapeutic targets in leukemia,” Children’s Hospital, Boston, with Todd R. Golub, MD, Children’s Hospital, Boston, Massachusetts

Peter D. Cole, MD
Damon Runyon-Lilly Clinical Investigator
“Improving the therapeutic index for children with acute lymphoblastic leukemia through studies of folate physiology and antifolate pharmacodynamics” with I. David Goldman, MD, Albert Einstein College of Medicine, Bronx, New York

Dean W. Felsher, MD, PhD
Damon Runyon-Lilly Clinical Investigator
“Targeting MYC for the treatment of lymphoma” with Ronald Levy, MD, Stanford University School of Medicine, Stanford, California

Pierre P. Massion, MD
Damon Runyon-Lilly Clinical Investigator
“Proteomic approach for risk assessment of lung cancer” with David P. Carbone, MD, PhD, Vanderbilt University Medical Center, Nashville, Tennessee

Jedd D. Wolchok, MD, PhD
Damon Runyon-Lilly Clinical Investigator
“Clinical development of DNA vaccines for melanoma” with Alan N. Houghton, MD, Memorial Sloan-Kettering Cancer Center, New York, New York

2002 Recipients (Five-Year Awards)

Madhav V. Dhodapkar, MD
Damon Runyon-Lilly Clinical Investigator
“Anti-tumor immunity in myeloma” with Ralph M. Steinman, MD, The Rockefeller University, New York, New York

William M. Grady, MD
Damon Runyon-Lilly Clinical Investigator
“Novel molecular screening and surveillance methods for colorectal cancer” with John D. Potter, MD, PhD, Fred Hutchinson Cancer Research Center, Seattle, Washington

Albert C. Koong, MD, PhD
Damon Runyon-Lilly Clinical Investigator
“Modulation of protein kinase C as a novel hypoxia-specific therapeutic strategy” with Sarah S. Donaldson, MD, and Amato J. Giaccia, PhD, Stanford University School of Medicine, Stanford, California

James M. Olson, MD, PhD
Damon Runyon-Lilly Clinical Investigator
“Predicting retinoid-responsive medulloblastoma patients” with Jeffrey Russell Geyer, MD, and Stephen J. Tapscott, MD, PhD, Fred Hutchinson Cancer Research Center, Seattle, Washington

Sridhar Mani, MD
Damon Runyon-Lilly Clinical Investigator
“Molecular and phenotypic dose adaptation models in the clinical development of novel microtubule binding agents” with Roman Perez-Soler, MD, and Susan B. Horwitz, PhD, Albert Einstein College of Medicine, New York, New York

2001 Recipients (Five-Year Awards)

Joseph A. Califano, III, MD
Damon Runyon-Lilly Clinical Investigator
“Molecular screening in a population at risk for head and neck cancer” with David Sidransky, MD, and Anthony J. Alberg, PhD, MPH, The Johns Hopkins University School of Medicine, Baltimore, Maryland

Li Li, MD, PhD
Damon Runyon-Lilly Clinical Investigator
“Diet, methylenetetrahydrofolate reductase, genomic DNA methylation, and five most promising novel candidate genes in the carcinogenesis of colon neoplasia” with Sanford Markowitz, MD, PhD, Case Western Reserve University, Cleveland, Ohio

Jennifer L. Malin, MD
Damon Runyon-Lilly Clinical Investigator
“Quality of chemotherapy care for cancer: evaluating underuse, overuse and misuse” with Katherine L. Kahn, MD, University of California School of Medicine, Los Angeles, California

William R. Sellers, MD
Damon Runyon-Lilly Clinical Investigator
“The molecular classification of prostate cancer” with David M. Livingston, MD, Dana-Farber Cancer Institute, Boston, Massachusetts

Cassian Yee, MD
Damon Runyon-Lilly Clinical Investigator
“Adoptive T-cell therapy of melanoma” with Philip D. Greenberg, MD, Fred Hutchinson Cancer Research Center, Seattle, Washington

2000 Recipients (Five-Year Awards)

Rafael Fonseca, MD
Damon Runyon-Lilly Clinical Investigator
“Genomic instability in plasma cell dyscrasias,” Mayo Clinic, Scottsdale, Arizona, with Philip R. Greipp, MD, Mayo Clinic, Rochester, Minnesota

Maura L. Gillison, MD, PhD
Damon Runyon-Lilly Clinical Investigator
“Establishing a casual association between HPV and HNSCC” with Keerti V. Shah, MD, DrPH, The Johns Hopkins University School of Medicine, Baltimore, Maryland

Vered Stearns, MD
Damon Runyon-Lilly Clinical Investigator
“Surrogate markers as endpoints: novel clinical design for combining standard and novel therapies in breast cancer” with Nancy E. Davidson, MD, The Johns Hopkins University School of Medicine, Baltimore, Maryland

Robert H. Vonderheide, MD, PhD
Damon Runyon-Lilly Clinical Investigator
“Clinical evaluation of telomerase as a widely expressed tumor-associated antigen linked to oncogenesis” with Carl H. June, MD, University of Pennsylvania, Philadelphia, Pennsylvania

Edus “Hootie” Warren, MD, PhD
Damon Runyon-Lilly Clinical Investigator
“Antigen-specific T-cell therapy for leukemia” with Stanley R. Riddell, MD, Fred Hutchinson Cancer Research Center, Seattle, Washington