Innovators

(Three-year Awards)

2011 Recipients

Alexei A. Aravin, PhD
“Epigenetic regulation of transposable elements in cancer” California Institute of Technology, Pasadena, California

James E. Bradner, PhD
“Targeting epigenetic readers as cancer therapy” Dana-Farber Cancer Institute, Boston, Massachusetts

Joshua E. Elias, PhD
“How cancers cope with damage: a proteomics approach” Stanford University School of Medicine, Stanford, California

Benjamin P. Tu, PhD
“A novel strategy for attacking tumors based on the identification of a fundamental carbon-source signal driving cell growth” University of Texas Southwestern Medical Center, Dallas, Texas

Matthew G. Vander Heiden, MD, PhD
“Understanding the metabolic requirements of cancer cells” Massachusetts Institute of Technology, Cambridge, Massachusetts

2010 Recipients

Heather R. Christofk, PhD
“Regulation of cancer metabolism” University of California, Los Angeles, California

Joshua C. Munger, PhD
“Elucidating mechanisms of oncogenic metabolic manipulation” University of Rochester, Rochester, New York

Raffaella Sordella, PhD
“Characterization of Erlotinib resistant, Mesenchymal and Metastatic (EMM) cells present in naïve lung tumors prior to treatments” Cold Spring Harbor Laboratory, Cold Spring Harbor, New York

2009 Recipients

Ivan Maillard, MD, PhD, (and Yi Zhang, MD, PhD)
“Modulation of Notch signaling to control graft-versus-host-disease and preserve the anti-tumor activity of alloreactive T cells” University of Michigan, Ann Arbor, Michigan

John L. Rinn, PhD
“The functional roles of large intergenic non-coding RNAs in cancer” Beth Israel Deaconess Medical Center, Boston, Massachusetts

Muneesh Tewari, MD, PhD
“Cancer detection in ‘pre-diagnosis’ blood samples via exosome-associated small RNAs” Fred Hutchinson Cancer Research Center, Seattle, Washington

Yi Zhang, MD, PhD, (and Ivan Maillard, MD, PhD)
“Modulation of Notch signaling to control graft-versus-host-disease and preserve the anti-tumor activity of alloreactive T cells” University of Michigan, Ann Arbor, Michigan

2008 Recipients

Nathanael S. Gray, PhD
“Identification of kinase substrates using selective irreversible crosslinkers” Dana-Farber Cancer Institute, Boston, Massachusetts

David G. Kirsch, MD, PhD
“Transforming cancer therapy with molecular imaging” Duke University, Durham, North Carolina