2015 New Discoveries and Honors in Cancer Research

2015 New Discoveries and Honors in Cancer Research

2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005

Members of the Damon Runyon scientific circle regularly publish findings on the latest cancer research and are frequently recognized for their contributions to the fight against cancer.  Below, you will find new discoveries in cancer research and the most recent honors bestowed upon Damon Runyon Cancer Research Foundation awardees, alumni and friends.

2013 New Discoveries and Honors in Cancer Research

2013 New Discoveries and Honors in Cancer Research

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005

Members of the Damon Runyon scientific circle regularly publish findings on the latest cancer research and are frequently recognized for their contributions to the fight against cancer.  Below, you will find new discoveries in cancer research and the most recent honors bestowed upon Damon Runyon Cancer Research Foundation awardees, alumni and friends.

2014 New Discoveries and Honors in Cancer Research

2014 New Discoveries and Honors in Cancer Research

2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005

Members of the Damon Runyon scientific circle regularly publish findings on the latest cancer research and are frequently recognized for their contributions to the fight against cancer.  Below, you will find new discoveries in cancer research and the most recent honors bestowed upon Damon Runyon Cancer Research Foundation awardees, alumni and friends.

2012 New Discoveries and Honors in Cancer Research

2012 New Discoveries and Honors in Cancer Research

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005

Members of the Damon Runyon scientific circle regularly publish findings on the latest cancer research and are frequently recognized for their contributions to the fight against cancer.  Below, you will find new discoveries in cancer research and the most recent honors bestowed upon Damon Runyon Cancer Research Foundation awardees, alumni and friends.

2011 New Discoveries and Honors in Cancer Research

2011 New Discoveries and Honors in Cancer Research

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005

Members of the Damon Runyon scientific circle regularly publish findings on the latest cancer research and are frequently recognized for their contributions to the fight against cancer.  Below, you will find new discoveries in cancer research and the most recent honors bestowed upon Damon Runyon Cancer Research Foundation awardees, alumni and friends.

2010 New Discoveries and Honors in Cancer Research

2010 New Discoveries and Honors in Cancer Research

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005

Members of the Damon Runyon scientific circle regularly publish findings on the latest cancer research and are frequently recognized for their contributions to the fight against cancer.  Below, you will find new discoveries in cancer research and the most recent honors bestowed upon Damon Runyon Cancer Research Foundation awardees, alumni and friends.

2009 New Discoveries and Honors in Cancer Research

2009 New Discoveries and Honors in Cancer Research

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005

Members of the Damon Runyon scientific circle regularly publish findings on the latest cancer research and are frequently recognized for their contributions to the fight against cancer.  Below, you will find new discoveries in cancer research and the most recent honors bestowed upon Damon Runyon Cancer Research Foundation awardees, alumni and friends.

2005 New Discoveries and Honors in Cancer Research

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005

Members of the Damon Runyon scientific circle regularly publish findings on the latest cancer research and are frequently recognized for their contributions to the fight against cancer.  Below, you will find new discoveries in cancer research and the most recent honors bestowed upon Damon Runyon Cancer Research Foundation awardees, alumni and friends.

2006 New Discoveries and Honors in Cancer Research

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005

Members of the Damon Runyon scientific circle regularly publish findings on the latest cancer research and are frequently recognized for their contributions to the fight against cancer.  Below, you will find new discoveries in cancer research and the most recent honors bestowed upon Damon Runyon Cancer Research Foundation awardees, alumni and friends.

2007 New Discoveries and Honors in Cancer Research

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005

Members of the Damon Runyon scientific circle regularly publish findings on the latest cancer research and are frequently recognized for their contributions to the fight against cancer.  Below, you will find new discoveries in cancer research and the most recent honors bestowed upon Damon Runyon Cancer Research Foundation awardees, alumni and friends.

2008 New Discoveries and Honors in Cancer Research

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005

Members of the Damon Runyon scientific circle regularly publish findings on the latest cancer research and are frequently recognized for their contributions to the fight against cancer.  Below, you will find new discoveries in cancer research and the most recent honors bestowed upon Damon Runyon Cancer Research Foundation awardees, alumni and friends.

Damon Runyon Cancer Research Foundation Announces First Recipients of New Physician-Scientist Award

Grants totaling nearly $1.4M give three physician-scientists resources to pursue cancer research


New York, NY (June 30, 2015) – Physician-scientists are crucial to moving scientific discoveries from the lab to patients, but their numbers have been dwindling just when they are needed most, particularly in cancer research, as the number of cancer cases is projected to increase by 45 percent in the next fifteen years and elevate cancer to the leading cause of death in America.

“Physician-scientists have the unique capacity to blend their insights from treating patients and working in the laboratory in a way that enables and accelerates medical advances,” said Yung S. Lie, PhD, Deputy Director and Chief Scientific Officer of the Damon Runyon Cancer Research Foundation. “If the present shortage of physician-scientists continues, we risk a situation in which some major laboratory research discoveries may not reach patients at all, and that would represent a true crisis in cancer research.” 

To help increase the number of physician-scientists, the Damon Runyon Cancer Research Foundation (Damon Runyon) has created a new award, the Damon Runyon Physician-Scientist Training Award, which provides physicians who have earned an MD degree and completed clinical specialty fellowship training the opportunity to gain the research skills and experience they need to become leaders in translational and clinical research.

Damon Runyon seeks to address the financial disincentives that often deter physicians from pursuing a research career by providing considerably higher funding than most research fellowships—$100,000 in the first year, with increases of $10,000 per year over the next three years. It will also retire up to $100,000 of any medical school debt still owed by an award recipient. (The average medical school debt is now more than $150,000.)

Damon Runyon announced that three scientists with novel approaches to fighting cancer have been named the 2015 recipients of the Damon Runyon Physician-Scientist Training Award. The awardees were selected through a highly competitive and rigorous process by a scientific committee comprised of leading cancer researchers who are themselves physician-scientists. Only those scientists showing exceptional promise and a passion for finding new cures for cancer were selected to receive the award.

“Too often, medical students and recent graduates discover their passion for research when it is too late to join an MD-PhD program or otherwise acquire the experience they need to pursue a research career,” said Lorraine W. Egan, President and CEO of Damon Runyon. “Physicians are essential to cancer research but often lack the opportunity and grant support needed to become researchers. We felt it was important to create that opportunity and hope that other organizations will use this award as a model.”

The Physician-Scientist Training Award was established thanks to the generosity of Damon Runyon Board members Leon Cooperman and Michael Gordon.

2015 Damon Runyon Physician-Scientist Training Award Recipients:


Pavan Bachireddy, MD
with Mentor Catherine J. Wu, MD, at Dana-Farber Cancer Institute, Boston, Massachusetts

Patients with relapsed blood cancers after allogeneic stem cell transplant are often treated with donor lymphocyte infusion (DLI), a type of immunotherapy that boosts the anti-tumor response and aims to induce cancer remission. The success of DLI varies from patient to patient. Dr. Bachireddy aims to investigate the determinants of DLI success and failure by studying the leukemic and immune cells during response to immunotherapy. Careful study of successful anti-tumor immune responses may reveal insights into tumor-immune interactions that may be relevant to predicting patient response to novel immunotherapies in other tumors.

Carolyn C. Jackson, MD
with Mentor Jean-Laurent Casanova, MD, PhD, at Memorial Sloan Kettering Cancer Center, New York, New York

Kaposi sarcoma (KS), a potentially fatal cancer especially in immunodeficient individuals, is caused by human herpes virus-8 (HHV-8), a carcinogenic agent declared by the World Health Organization. Human genetic variability may account for the variability in the clinical outcome of HHV-8 infection. Dr. Jackson aims to discover novel genetic alterations underlying childhood KS and to understand how specific gene defects drive KS in conjunction with HHV-8. The genetic study of KS in childhood may provide new insights into the pathogenesis of KS, and aid in developing potential future therapeutics. It will also benefit children at risk of KS in regions of the world where the prevalence of HHV-8 is high.

Loretta S. Li, MD
with Mentor David Weinstock, MD, at Dana-Farber Cancer Institute, Boston, Massachusetts

Approximately 10-15% of pediatric and adult patients with B-cell acute lymphoblastic leukemia (B-ALL) have a high-risk form of the disease characterized by rearrangements of a gene called CRLF2. Alterations of this gene result in increased expression of the CRLF2 protein and promote leukemia development. When treated with conventional chemotherapy, patients with CRLF2 gene alterations do poorly. Their leukemias are dependent on an enzyme called JAK2 for survival, yet no targeted therapies with proven efficacy are currently available. Dr. Li has unique access to a new drug that turns off JAK2 enzyme activity, potently kills B-ALL cells, and improves overall survival in mice with JAK2-dependent B-ALL. Treatment with this drug alone is not curative, however, and all mice eventually succumb to progressive leukemia. She will study how leukemia becomes resistant to JAK2 inhibitors. Her goal is to identify combinations of agents that can prevent or overcome resistance to a single therapy and also guide the development of new JAK2 inhibitors for patients.

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DAMON RUNYON CANCER RESEARCH FOUNDATION

To accelerate breakthroughs, the Damon Runyon Cancer Research Foundation provides today's best young scientists with funding to pursue innovative research. The Foundation has gained worldwide prominence in cancer research by identifying outstanding researchers and physician-scientists. Twelve scientists supported by the Foundation have received the Nobel Prize, and others are heads of cancer centers and leaders of renowned research programs. Each of its award programs is extremely competitive, with less than 10% of applications funded. Since its founding in 1946, the Foundation has invested $294 million and funded more than 3,500 young scientists. This year it will commit almost $15 million in new awards to brilliant young investigators.

100% of all donations to the Foundation are used to support scientific research. Its administrative and fundraising costs are paid from its Damon Runyon Broadway Tickets Service and endowment.

CONTACT
Yung S. Lie, PhD
Deputy Director and Chief Scientific Officer
Damon Runyon Cancer Research Foundation
yung.lie@damonrunyon.org
212.455.0521

 

2015 Annual Breakfast Honoring Dmitri Stockton Raises $1.5 Million

New York, NY (May 5, 2015) - The Damon Runyon Cancer Research Foundation honored Dmitri Stockton, President and CEO of GE Asset Management, at its 2015 Annual Breakfast, held on Tuesday morning at Cipriani 42nd Street in New York City. The Breakfast raised $1.5 million to support the nation’s best and brightest cancer researchers, fostering the talent capable of revolutionizing the prevention, detection, and treatment of all forms of cancer.

Alan M. Leventhal, Chairman of the Damon Runyon Board, welcomed attendees by noting the scope and ambition of Damon Runyon scientists, saying, “There’s nobody who does what Damon Runyon does in the quest to cure cancer. We don’t worry about one cancer, we worry about them all.”

Two exceptional Damon Runyon scientists illustrated Damon Runyon’s wide range of focus with research updates: Damon Runyon-Sohn Pediatric Cancer Fellow Angela J. Waanders, MD, of The Children’s Hospital of Philadelphia, spoke about her efforts to develop more effective, less toxic treatments for childhood glioma brain tumors, and Damon Runyon-Rachleff Innovator Moritz F. Kircher, MD, PhD, of Memorial Sloan Kettering Cancer Center, walked attendees through his development of a precision tool that detects and enables the destruction of single cancer cells during surgery.

The event’s keynote speaker was John Elway, former NFL star and current Denver Broncos General Manager. Elway spoke emotionally about losing his twin sister to lung cancer 14 years ago. “Cancer is the ultimate competitor,” he said, exhorting those listening to commit as much support as possible to the Damon Runyon scientists who have dedicated their careers to cancer research. “This foundation has established a roster that reads like an All-Pro team. They are making a difference.”

The morning's honoree, Dmitri Stockton, was introduced by Leon G. Cooperman, who is the Chairman and CEO of Omega Advisors and a current Damon Runyon Board of Directors member.

Stockton shared cancer's impact on his friends and family and expressed great hope for the future. Gesturing to the Damon Runyon scientists in attendance, he said, “I've met these scientists and I can tell you, they’re nothing short of incredible. These are some of the minds who have dedicated themselves to fighting cancer. The impact they’re going to have in the future is just phenomenal. I want you to remember the stories here today and keep up with the fight by funding these scientists."

DAMON RUNYON CANCER RESEARCH FOUNDATION

To accelerate breakthroughs, the Damon Runyon Cancer Research Foundation provides today’s best young scientists with funding to pursue innovative research. The Foundation has gained worldwide prominence in cancer research by identifying outstanding researchers and physician-scientists. Twelve scientists supported by the Foundation have received the Nobel Prize, seven others have received National Medals of Science, and 68 have been elected to the National Academy of Sciences.

Since its founding in 1946, Damon Runyon has invested nearly $294 million and funded nearly 3,500 young scientists. One hundred percent of all donations to the Foundation are used to support cutting-edge scientific research. Its administrative and fundraising costs are paid from its Damon Runyon Broadway Tickets and endowment.


CONTACT

Kim Kubert
Damon Runyon Cancer Research Foundation
212.455.0501
kim.kubert@damonrunyon.org 

May 7, 2015 > Pershing Square Sohn Prizes for Young Investigators in Cancer Research

The Pershing Square Sohn Cancer Research Alliance has announced the winners of the 2015 Pershing Square Sohn Prize for Young Investigators in Cancer Research. The annual prize aims to catalyze collaboration among young investigators, academics, nonprofits, investors, and the biotech and pharmaceutical industries. The prize-winners will each receive funding for up to three years. Three of the six awards were granted to Damon Runyon scientists:

Arvin C. Dar, PhD (Damon Runyon-Rachleff Innovator ’14-’16), Icahn School of Medicine at Mount Sinai, New York
Moritz F. Kircher, MD, PhD (Damon Runyon-Rachleff Innovator ’14-’16), Memorial Sloan Kettering Cancer Center, New York
Christine Mayr, PhD (Damon Runyon-Rachleff Innovator ’13-’15), Memorial Sloan Kettering Cancer Center, New York

Click here for more.

Runyon 5K—Run/Walk for Cancer Research

Runyon 5K For Cancer Research at Yankee StadiumAfter five years of summer fun at Yankee Stadium, the Runyon 5K is returning to its November roots in 2015! Mark your calendar: the seventh annual Damon Runyon 5K at Yankee Stadium will be held on Sunday, November 15. Thousands of baseball fans, runners, walkers, cancer survivors, and their friends and family will gather at Yankee Stadium to raise funds for cancer research. One of New York's most unique summer events, the Runyon 5K is the only charitable run/walk that uses the iconic Stadium as its course. As always, 100% of donations raised at the Runyon 5K will directly support the innovative young scientists funded by the Damon Runyon Cancer Research Foundation. Since inception, the event has raised more than $3.5 million. 


If you would like to be added to our email list to receive news and updates about the 2015 Runyon 5K, please sign up for our Runyon 5K Email Alert.

See photos from the 2014 Runyon 5K.

See videos on Youtube from the 2014 Runyon 5K.

April 28, 2015 > New members of National Academy of Sciences elected

Election to the National Academy of Sciences is one of the highest honors that can be earned by a U.S. scientist.  In recognition of their distinguished and continuing achievements in original biomedical research, members of the Damon Runyon community of scientists were inducted this April:   
DAMON RUNYON FELLOWS
Brenda L. Bass, PhD (Damon Runyon Fellow ’85-’88), University of Utah School of Medicine, Salt Lake City
Jeffery F. Miller, PhD (Damon Runyon Fellow '86-’89), University of California, Los Angeles
Danny F. Reinberg, PhD (Damon Runyon Fellow ’83-’85), New York University School of Medicine, New York City


DAMON RUNYON AWARD COMMITTEE MEMBERS
Riccardo Dalla-Favera, MD (Former Fellowship Award Committee Guest Reviewer), Columbia University, New York City
Catherine Dulac, PhD (Former Fellowship Award Committee, Former Sponsor), Harvard University, Cambridge
Maria Jasin, PhD (Current Pediatric Cancer Fellowship Award Committee, Former Fellowship Award Committee, Former Sponsor), Memorial Sloan Kettering Cancer Center, New York City
Rodney J. Rothstein, PhD (Former Fellowship Award Committee), Columbia University Medical Center, New York City
Jeremy W. Thorner, PhD (Former Fellowship Award Committee, Former Sponsor), University of California, Berkeley

Click here for more.

April 24, 2015 > Prestigious cell biology prize awarded

Elaine V. Fuchs, PhD (Damon Runyon Board Member, Damon Runyon Fellow ‘77-‘79) of The Rockefeller University, New York, has received the E.B. Wilson Medal, the highest scientific honor bestowed by the American Society for Cell Biology. She is recognized for her pioneering research on mammalian skin and adult stem cells.

Click here for more.

April 20, 2015 > Combination therapy for treatment of advanced melanoma

Jedd D. Wolchok, MD, PhD (Damon Runyon-Lilly Clinical Investigator ‘03-‘08) and colleagues at Memorial Sloan Kettering Cancer Center, New York, reported the results of a Phase I study testing a combination therapy (Yervoy plus Opdivo/nivolumab) vs. Yervoy alone in patients with metastatic melanoma (with wild type BRAF gene).  In 72 patients, the rate of confirmed response was 61% for the combination therapy (22% with complete response) vs. 11% for Yervoy alone (0% complete response).  These results were published in the journal The New England Journal of Medicine.   

Click here for more.

The William Raveis Ride + Walk

The William Raveis Ride + Walk

Ride + Walk to Fund Cancer Research
We are proud to partner with William Raveis Real Estate, Mortgage, & Insurance for The William Raveis Ride + Walk, which will be held in Hingham, MA on Saturday, August 22, 2015, and in Fairfield, CT on Saturday, September 12, 2015. You can register as an individual or as part of a team to participate in a 12-mile bike ride, 25-mile bike ride, or a 5K walk. Join with friends and family for a fun-filled day to raise funds for cancer research, with 100% of all donations benefiting the Damon Runyon Cancer Research Foundation. Click here for more information.

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