Damon Runyon Cancer Resources

June 15, 2010 > Pathways identified in metastatic lung cancer

William Y. Kim, MD (Damon Runyon-Merck Clinical Investigator ‘09-‘12) of the University of North Carolina, Chapel Hill, and colleagues reported that the SRC, PI3K and MEK1/2 kinase signaling pathways act together in metastatic lung tumors that have deletions of the tumor suppressor LKB1.  These findings suggest that unique combinatorial therapies may be successful for treatment of lung cancers.  The research was published in the journal Cancer Cell.    

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