Damon Runyon Cancer Research Foundation - Latest Cancer Research Discoveries

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July 21, 2006

Anita G. Seto, PhD (Damon Runyon Fellow '03-'06) and colleagues reported on a new complex of small RNAs, termed piRNAs and regulatory proteins in the prestigious journal Science. While the precise function of this complex is not yet clear, it is likely involved in controlling how certain genes are turned off or "silenced." This discovery has numerous implications for cancer research, as the silencing of cellular brakes called tumor suppressor genes is a critical step cancer development.