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May 21, 2010 > Silica cages used for improved cancer drug delivery
Jun Liu, PhD (Damon Runyon Fellow ‘91-‘93) and colleagues at Pacific Northwest National Laboratory, Richland, reported that anti-cancer drugs (antibodies) can be packaged into silica particles for more efficient delivery to the tumor. The particles were injected directly into a mouse melanoma, which resulted in much greater and prolonged inhibition of tumor growth than the antibody given systemically. These studies present a promising new approach for local targeted delivery of drugs to tumors. The findings were published in the Journal of the American Chemical Society.