To accelerate breakthroughs, the Damon Runyon Foundation provides today's best young scientists with funds to pursue innovative cancer research.
- Today’s Promising Areas of Cancer Research
- What is Cancer?
- A Broken Pipeline?
A Generation of Science at Risk
- ARISE Report
Early Career Scientists and High-Risk, High Reward Research - American Academy of Arts and Sciences
- Why We’re Losing the War on Cancer (And How To Win It)
Clifton Leaf - Fortune Magazine
May 4, 2010 > Novel understanding of cell invasion process
David Q. Matus, PhD (Damon Runyon Fellow ‘07-‘10) and colleagues at Duke University, Durham, identified novel genes involved in cell invasion of basement membranes, a process essential during development, immune surveillance, and metastasis. Basement membranes form the lining of blood vessels and organs in the body. The researchers found that turning off two specific genes, cct-5 and lit-1, in metastatic carcinoma cells reduced the cells’ ability to invade these basement membranes. The results, published in the journal Science Signaling, may provide new therapeutic targets to control cell invasion and metastasis in cancer.