Damon Runyon Cancer Resources

November 5, 2009 > First use of an antibody to deliver targeted radiation to leukemia patients

John M. Pagel, MD, PhD (Damon Runyon-Lilly Clinical Investigator ‘05-‘10) of the Fred Hutchinson Cancer Research Center, Seattle, reported the success of a Phase I clinical trial testing a novel combination of low-intensity chemotherapy, targeted radiation delivery by an antibody and a stem cell transplant.  This regimen resulted in remission for patients with advanced acute myeloid leukemia or a pre-leukemia syndrome.  These are patients for whom there previously had been no other treatment options.  The report was published in the journal Blood

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