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September 2, 2009 > Studies on the mechanisms of drug resistance in leukemia
Neal G. Copeland, PhD (Damon Runyon Fellow ‘77-‘79) and Nancy A. Jenkins, PhD (Former Fellowship Sponsor) of the Institute of Molecular and Cell Biology, Singapore, and Luis F. Parada, PhD (Damon Runyon Fellow ‘85-‘86, former Fellowship Advisory Committee Member) of University of Texas Southwestern, Dallas, and colleagues reported a new strategy to study the mechanism of drug resistance in leukemia and other cancers. The researchers developed an animal model that allows them to identify new genetic mutations that are linked to resistance. A greater understanding of resistance will enable the development of ways to anticipate and overcome drug resistance, leading to more effective therapies. This report was published in the journal Nature.