Ralph J. DeBerardinis, MD, PhD (Damon Runyon Clinical Investigator ‘11-‘14) of UT Southwestern Medical Center, Dallas, and colleagues, discovered a metabolic pathway unique to some tumors.  The tumor-specific pathway is dependent on the amino acid glutamine and reverses many of the chemical reactions of the Krebs cycle, used by normal cells.  This new finding could provide a new target for drugs that could specifically target cancer cells without harming healthy cells.  The study was published in the scientific journal Nature.

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