Dr. Wilson is developing molecular tools to specifically modify RNA as a potential pathway to novel cancer therapeutics. RNA modification affects RNA fate and influences the way genes are expressed, including cell cycle control, cell differentiation, and transcript stability, which have been linked to a variety of diseases, including cancer. Dr. Wilson aims to use the CRISPR/Cas9 homologs to alter RNA translation, ultimately leading to an increased understanding of the role of the transcriptome— all of the messenger RNA molecules expressed from the genes of an organism.
Damon Runyon Researchers
Meet Our Scientists
Christopher Wilson, PhD
Project title: "Development of a programmable writer and eraser of m6A RNA methylation"
Institution: Harvard University
Named Award: HHMI Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): David R. Liu, PhD
Cancer Type: All Cancers
Research Area: RNA (RNA processing, miRNA and piRNA mechanisms, enzymatic RNAs, etc.)
