Damon Runyon Researchers

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Dian Yang, PhD

Dr. Yang is examining tumor heterogeneity in search of new diagnostic markers and potential therapeutic targets. A tumor consists of not only cancer cells, but also immune cells, fibroblasts and other stromal components. The diverse cell types and cell states may promote disease progression and lead to therapeutic resistance, which is one of the greatest challenges in precision medicine. Dr. Yang aims to understand how heterogeneity is generated and regulated by using single cell functional genomic tools.

Project title: "Dissecting intratumoral heterogeneity and hierarchy at single cell resolution"
Institution: Whitehead Institute for Biomedical Research
Award Program: Fellow
Sponsor(s) / Mentor(s): Jonathan S. Weissman, PhD, and Trever G. Bivona, MD, PhD
Cancer Type: Lung
Research Area: Cancer Genetics