Damon Runyon Researchers

Dr. Bhabha is focusing on understanding the function of structures on the cell surface called cilia, which play important roles in signaling, sensing the cell’s environment, and regulating cell growth. One particular signaling pathway in cilia, Hedgehog, has been shown to be dysregulated in multiple cancers, including basal cell carcinoma, medulloblastoma, and pancreatic cancer. She aims to characterize the structure and dynamics of the large, multi-protein complexes that function within the cilia. These findings will give insight into the role of cilia in cancers.