Damon Runyon Researchers

Meet Our Scientists
Yuxiang Zhang, MD, PhD

Dr. Zhang is studying the mechanisms that promote recurrent DNA double strand break clusters (RDCs) in the brain and liver, and how these breaks in the DNA are repaired to maintain genomic stability and suppress tumors. Recently, RDCs were found in neural stem and progenitor cells. This work may reveal if DNA breaks in RDC genes predispose individuals to genomic variations that could contribute to cancers and other diseases.

Project title: "Mechanisms that promote DNA double strand break clusters in brain and liver"
Institution: Boston Children's Hospital
Named Award: HHMI Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Frederick W. Alt, PhD
Cancer Type: All Cancers
Research Area: Genomics