Damon Runyon Researchers

Meet Our Scientists
Michael A. Cianfrocco, PhD

Dr. Cianfrocco [HHMI Fellow] studies proteins called dynactin and dynein that function to transport organelles within the cell, a process that is particularly important during cell division. He aims to elucidate the structural basis for dynactin's ability to regulate dynein activity. Since many viruses, including cancer-causing oncoviruses, require dynein to be transported from the cell membrane to the nucleus for genome replication, understanding the molecular details of dynein-dynactin function may provide novel targets for cancer therapies. 

Project title: "How does dynein achieve processivity?"
Institution: University of California, San Diego
Named Award: HHMI Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Andres Leschziner,PhD, and Samara L. Reck-Peterson, PhD
Cancer Type: Gynecological, Other Cancer
Research Area: Structural Biology