New Discoveries and Honors in Cancer Research

Read the latest cancer research and recognition from the members of the Damon Runyon scientific circle.
October 9, 2011
Role for Hedgehog signaling pathway in lung cancer

Julien Sage, PhD (Damon Runyon Scholar ‘05-‘07) of Stanford University, Stanford, and colleagues, reported a crucial role for Hedgehog signaling in the development of small-cell lung cancer (SCLC). They demonstrated that blocking Hedgehog signaling inhibited the growth of SCLC, particularly after chemotherapy. Their findings suggest that Hedgehog pathway inhibition may be a promising therapeutic strategy to slow disease progression and delay cancer recurrence in SCLC patients. This study was published in the journal Nature Medicine.