Cameron J. Turtle, MD, PhD (Damon Runyon Clinical Investigator ’13-’16) and colleagues at the Fred Hutchinson Cancer Research Center, Seattle, successfully refined a cancer immunotherapy treatment, resulting in no detectable disease in 27 of 29 adult patients (93%) with B-cell acute lymphoblastic leukemia, or ALL. The pioneering technique uses two subsets of genetically engineered immune T-cells from the patient (CD19 CAR-T cells) to target and attack the cancer. The promising results were published in the Journal of Clinical Investigation.
