Damon Runyon Researchers

Dr. Lyssiotis focuses on how oncogenes affect cellular metabolism in pancreatic cancer. In particular, he is interested in understanding how mutations in the oncogene Kras alter cellular metabolism in pancreatic ductal adenocarcinoma to facilitate cell growth. He will determine if distinct components of Kras-mediated signaling can be targeted for therapeutic gain. Ultimately, this work aims to translate our understanding of pancreatic cancer cell metabolism into therapies for this devastating disease.