Dr. Dann is studying how the addition of the amino acid arginine to proteins regulates their biological activity. When this process malfunctions, cancerous genes are transcribed into proteins. Dr. Dann will use high-resolution mass spectrometry to identify arginine-modified proteins in cells, chemical biological tools to decipher the role of such modification in determining protein function, and functional genomics to understand how this process regulates the genome.
Damon Runyon Researchers
Meet Our Scientists
Geoffrey P. Dann, PhD
Project title: "Proteomics to bridge protein arginylation, chromatin, and cancer"
Institution: University of Pennsylvania, Philadelphia
Named Award: Merck Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Benjamin A. Garcia, PhD
Cancer Type: All Cancers
Research Area: Chromatin Biology
