Dr. Whicher focuses on a cellular structure called the voltage-gated potassium channel Eag1, which can promote tumor growth and is aberrantly expressed in many types of cancer including breast, colon, prostate, lung, and liver. He is determining the structure and mechanism of Eag1 in order to elucidate how Eag1 promotes cancer growth, with the eventual goal of developing Eag1 modulators as potential anti-cancer therapies.
Damon Runyon Researchers
Meet Our ScientistsJonathan R. Whicher, PhD
Project title: "Structure and mechanism of the voltage-gated potassium channel hEag1"
Institution: The Rockefeller University
Named Award: GE Asset Management Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Roderick MacKinnon, MD
Cancer Type: All Cancers
Research Area: Structural Biology