Current and Former Awardees

Innovators

2018 Recipients

Lawrence A. David, PhD
"Personalized prebiotics to optimize microbiota metabolism and improve transplant outcomes" at Duke University
Eric S. Fischer, PhD
"Novel mechanisms for small molecule induced targeted degradation of RRM family proteins" at Dana-Farber Cancer Institute
Arnold S. Han, MD, PhD
"Precision T cell receptor-based cancer therapies" at Columbia University
Amaia Lujambio, PhD
"Overcoming the resistantce to anti-PD1 immunotherapy in hepatocellular carcinoma" at Icahn School of Medicine at Mount Sinai
Wayne O. Miles, PhD
"Maximizing pro-apoptotic protein levels" at The Ohio State University
Anthony D. Sung, MD
"Personalized prebiotics to optimize microbiota metabolism and improve transplant outcomes" at Duke University

2017 Recipients

Benjamin L. Martin, PhD
"Cell cycle regulation of cellular behaviors associated with cancer metastasis" at Stony Brook University
David Q. Matus, PhD
"Cell cycle regulation of cellular behaviors associated with cancer metastasis" at Stony Brook University
Marcela V. Maus, MD, PhD
"Next-generation CAR-T cells for EGFRvIII-positive glioblastoma" at Massachusetts General Hospital
Rushika M. Perera, PhD
"Mechanisms of cellular transformation at the single organelle level" at University of California, San Francisco

2016 Recipients

Christin E. Burd, PhD
"Exploiting mutational specificity to target RAS-driven melanoma" at The Ohio State University
Jason M. Crawford, PhD
"Elucidating the bacterial determinants of colorectal cancer" at Yale University
Piero D. Dalerba, MD
"Using 'single-cell genomics' to resolve the molecular identity of 'cancer stem cells,' and guide their pharmacological eradication" at Columbia University
Scott J. Dixon, PhD
"Exploring the role of reductive stress in promoting cancer cell death" at Stanford University
Philip A. Romero, PhD
"Digital circulating tumor cell detection using scalable molecular logic" at University of Wisconsin, Madison
Peter J. Turnbaugh, PhD
"The gut microbiome: an unexpected contributor to cancer drug resistance" at University of California, San Francisco
Roberto Zoncu, PhD
"Identifying and disabling organelle circuits that fuel cancer cell metabolism" at University of California, Berkeley

2015 Recipients

Nicholas T. Ingolia, PhD
"Cis-regulatory code for the translational control of gene expression" at University of California, Berkeley
Christopher M. Jewell, PhD
"Harnessing intra-lymph node controlled release to study and enhance tumor immunity" at University of Maryland
Ning Jiang, PhD
"A single cell integrated system to dissecting cancer immunoediting in humans" at University of Texas, Austin
Guillem Pratx, PhD
"Adding a new dimension to flow cytometry: radionuclide-activated cell sorting" at Stanford University
Brian H. Shirts, MD, PhD
"Participatory genetics for defining genotype-phenotype associations of rare cancer variants" at University of Washington
Elçin Ünal, PhD
"Reducing cancer susceptibility by attenuating cellular aging" at University of California, Berkeley

2014 Recipients

Emily P. Balskus, PhD
"Understanding and preventing carcinogenesis caused by the human microbiota" at Harvard University
Arvin C. Dar, PhD
"Targeting allosteric control in the Ras-MAPK pathway for cancer therapy" at Icahn School of Medicine at Mount Sinai
Summer L. Gibbs, PhD
"Studying spatial regulation of HER2 tumorigenesis with multispectral super resolution microscopy (MSSRM)" at Oregon Health & Science University
Mortiz F. Kircher, MD, PhD
"Raman-MRI nanobeacons: towards a universal cancer theranostic agent" at Memorial Sloan Kettering Cancer Center
Xiaolin Nan, PhD
"Studying spatial regulation of HER2 tumorigenesis with multispectral super resolution microscopy (MSSRM)" at Oregon Health & Science University
Eirini Papapetrou, MD, PhD
"Dissecting chromosome hemizygosity with human pluripotent stem cells" at Icahn School of Medicine at Mount Sinai

2013 Recipients

Michael Z. Lin, MD, PhD
"Building the magic bullet: protein switches for sensing oncogenic signals and executing therapeutic programs" at Stanford University School of Medicine
Christine Mayr, MD, PhD
"A functional atlas of lymphoma specific aberrations generated by RNA processing" at Memorial Sloan Kettering Cancer Center
Nicholas E. Navin, PhD
"Developing single-cell sequencing methods to investigate metastatic seeding in breast cancer" at M.D. Anderson Cancer Center
Trudy G. Oliver, PhD
"Mechanisms of drug resistance in small cell lung cancer" at University of Utah
Bradley L. Pentelute, PhD
"Striking cancer with intracellular antibodies" at Massachusetts Institute of Technology
Agnel Sfeir, PhD
"Pathways involved in preserving the genomic stability of mitochondrial DNA" at New York University School of Medicine
Sarah (Sadie) M. Wignall, PhD
"Probing centrosome-clustering mechanisms to identify targets for new cancer therapies" at Northwestern University

2012 Recipients

Gregory L. Beatty, MD, PhD
“Targeting macrophages for cancer therapy” at University of Pennsylvania, Philadelphia
Jay R. Hesselberth, PhD
“Peptide identification by massively-parallel sequencing” at University of Colorado Denver
Matthew R. Pratt, PhD
“O-GIcNAc as a “sweet” link between metabolism and survival in cancer” at University of Southern California
Eranthie Weerapana, PhD
“Targeting reactive cysteine residues for cancer therapy” at Boston College
Feng Zhang, PhD
“Development and application of genome and epigenome engineering tools for cancer research” at The Broad Institute of MIT and Harvard

2011 Recipients

Alexei A. Aravin, PhD
“Epigenetic regulation of transposable elements in cancer” at California Institute of Technology
James E. Bradner, MD
“Targeting epigenetic readers as cancer therapy” at Dana-Farber Cancer Institute
Joshua E. Elias, PhD
“How cancers cope with damage: a proteomics approach” at Stanford University School of Medicine
Benjamin P. Tu, PhD
“A novel strategy for attacking tumors based on the identification of a fundamental carbon-source signal driving cell growth” at University of Texas Southwestern Medical Center
Matthew G. Vander Heiden, MD, PhD
“Understanding the metabolic requirements of cancer cells” at Massachusetts Institute of Technology

2010 Recipients

Heather R. Christofk, PhD
“Regulation of cancer metabolism” at University of California, Los Angeles
Joshua C. Munger, PhD
“Elucidating mechanisms of oncogenic metabolic manipulation” at University of Rochester
Raffaella Sordella, PhD
“Characterization of Erlotinib resistant, Mesenchymal and Metastatic (EMM) cells present in naïve lung tumors prior to treatments” at Cold Spring Harbor Laboratory

2009 Recipients

Ivan Maillard, MD, PhD (and Yi Zhang, MD, PhD)
“Modulation of Notch signaling to control graft-versus-host-disease and preserve the anti-tumor activity of alloreactive T cells” at University of Michigan, Ann Arbor
John L. Rinn, PhD
“The functional roles of large intergenic non-coding RNAs in cancer” at Beth Israel Deaconess Medical Center
Muneesh Tewari, MD, PhD
“Cancer detection in ‘pre-diagnosis’ blood samples via exosome-associated small RNAs” at Fred Hutchinson Cancer Research Center
Yi Zhang, MD, PhD (and Ivan Maillard, MD, PhD)
“Modulation of Notch signaling to control graft-versus-host-disease and preserve the anti-tumor activity of alloreactive T cells” at University of Michigan, Ann Arbor

2008 Recipients

Nathanael S. Gray, PhD
“Identification of kinase substrates using selective irreversible crosslinkers” at Dana-Farber Cancer Institute
David G. Kirsch, MD, PhD
“Transforming cancer therapy with molecular imaging” at Duke University Medical Center
Sarkis K. Mazmanian, PhD
“Host-bacterial immunomodulation in the development of cancer” at California Institute of Technology
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