Current Projects

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Cutting-edge research by the best and brightest

Damon Runyon cancer researchers work in technologically advanced labs and leading hospitals across the country.

Select a highlighted state to learn more about the scientists and projects that Damon Runyon is currently funding.

Scientists:

Alabama

Alaska

Arizona

Arkansas

California

University of California, Berkeley

"Filming mechanochemical cycles of ring ATPase: Phi 29 DNA packaging motor as an example"

University of California, Berkeley

Carissa Chan, PhD

"Control of gamma delta T cell anticancer activity by bacterial infection"

University of California, Berkeley

Yoshiki Sakai, PhD

"How do tumors evade cell extrusion?"

University of California, Berkeley

R. Camille Brewer, PhD

"Defining how early-life microbial encounters sculpt the B cell repertoire and shape vaccine responses"

University of California, Berkeley

Gabriel Cavin-Meza, PhD

"Leveraging polyploid Xenopus to probe spindle adaptation to increases in genome size"

University of California, Berkeley

Joshua B. Sheetz, PhD

"Mitochondrial ubiquitylation mechanisms to exploit metabolic vulnerabilities in cancer"

University of California, Berkeley

Ben F. Brian, PhD

"Mechanisms and consequences of microbiota-directed immune responses"

University of California, Berkeley

University of California, San Francisco

Daniel A. Waizman, PhD

"IL25 induced tissue resilience in the prevention of colorectal cancer and therapy-induced adverse events"

University of California, San Francisco

Hannah R. S. Martin, PhD

"Investigating the neural mechanisms that drive skeletal pain"

University of California, San Francisco

Jonathan Chou, MD, PhD

"Defining and exploiting the cancer surfaceome landscape for novel therapeutics"

University of California, San Francisco

Bridget P. Keenan, MD, PhD

"Improving outcomes for patients with hepatocellular carcinoma and liver disease by circumventing myeloid cell-mediated suppression"

University of California, San Francisco

Sue Im Sim, PhD

"Cellular structural biology of an evolutionarily-ancient organizer of cell shape and movement"

University of California, San Francisco

Rodrigo Gier, PhD

"Targeted chemical aggregation as a general strategy to overcome cancer drug resistance"

University of California, San Francisco

Matthew Decker, MD, PhD

"The N-Ras palmitoylation cycle as a therapeutic target in pediatric acute myeloid leukemia"

University of California, San Francisco

Kashish Jain, PhD

"Spatial mechanical regulation of oncogenic signaling in tumor progression and metastasis"

University of California, San Francisco

Philip T. Pauerstein, MD, PhD

"Enhancing immune synapse formation with synthetic adhesion to overcome chimeric antigen receptor-T cell resistance in pediatric B cell malignancies"

University of California, San Francisco

Sagar Bhattacharya, PhD

"De novo design of protease-activated anticancer proteins"

University of California, San Francisco

Shaohua Zhang, PhD

"Preventing tumor evasion of CAR T killing: engineering adhesion molecules to enhance cell immunotherapy"

University of California, San Francisco

Fanglue Peng, PhD

"Humanize CXCL13 expression in mouse to understand lymphoid neogenesis in cancer"

University of California, San Francisco

Youngmu (Nick) Shin, PhD

"Exploring phase condensation as a general mechanism for organizing cell-cell communication assemblies"

University of California, San Francisco

Tadashi Manabe, MD, PhD

"Characterization of oncogenic kinase signaling by membraneless cytoplasmic protein granules"

University of California, San Francisco

Erron W. Titus, MD, PhD

"Engineered cellular fusogens for novel immune effector functions"

University of California, San Francisco

David Y. Oh, MD, PhD

"Co-receptors modulating anti-tumor activity of human cytotoxic CD4+ effector cells"

University of California, San Francisco

Scripps Research Institute

Anna Karen Orta, PhD

"Structural and functional studies of ATAD3A: implications for mitochondrial maintenance and cancer progression"

Scripps Research Institute

The Salk Institute for Biological Studies

Matthew L. Miller, PhD

"Enter and persist: enhancing anti-tumor T-cell infiltration and metabolism in the brain"

The Salk Institute for Biological Studies

Wen Mai Wong, PhD

"Modulation of neuronal circuitry using sonogenetics"

The Salk Institute for Biological Studies

Stanford University

Kate M. MacDonald, PhD

"Formation, excision and cytoplasmic export mechanisms for pathological R-loops"

Stanford University

Xianfeng Zeng, PhD

"Microbiome-Cancer Connection: From Understanding to Rational Design with Defined Communities"

Stanford University

Mohammad Balood, PhD

"Development and evaluation of T cell receptor (TCR)-based immunotherapy to target pediatric Acute Megakaryoblastic Leukemia"

Stanford University

Laura Crowley, PhD

"Identifying fibroblast stem cells in organ maintenance, repair, and cancer"

Stanford University

David S. Roberts, PhD

"Defining the molecular landscape and native interactome of the Siglec-sialoglycan axis in disease"

Stanford University

Daniel J. Delitto, MD, PhD

"Pathogen sensing in fibroblasts restrains antitumor immunity in pancreatic cancer"

Stanford University

Felix C. Boos, PhD

"Inter-organ communication of protein homeostasis stress responses in vertebrate aging"

Stanford University

Debadrita Bhattacharya, PhD

"Investigating molecular and cellular mechanisms of intra-tumoral heterogeneity in small-cell lung cancer"

Stanford University

Lauren E. Cote, PhD

"Constructing one continuous digestive tract, cell by cell"

Stanford University

California Institute of Technology

Ling S. Loh, PhD

"Selfish persistence within a (super)organismal host"

California Institute of Technology

Dhiraj Indana, PhD

"Synthetic intercellular signaling circuits for threat sensing and response"

California Institute of Technology

"Understanding and engineering combinatorial gene regulation in mammalian cells"

California Institute of Technology

Georgia R. Squyres, PhD

"Spatiotemporal regulation of eDNA release in Pseudomonas aeruginosa biofilms"

California Institute of Technology

University of California, Los Angeles

Sohyeon Park, PhD

"Chromosome structure remodeling in innate immune training and gene regulation"

University of California, Los Angeles

Stanford University School of Medicine

Rongxin Fang, PhD

“Imaging and engineering of cellular communication in the brain and tumors”

Stanford University School of Medicine

Anita Reddy, PhD

"Elucidating the contributions of diet and exercise on the redox environment of the gut"

Stanford University School of Medicine

Simon Sretenovic, PhD

"High-throughput precision genome editing for dissecting complex traits in yeast and human cell lines"

Stanford University School of Medicine

Steven M. Corsello, MD

"Targeting intrinsic immune signaling in pancreatic cancer with small molecule therapeutics"

Stanford University School of Medicine

Jakob Wirbel, PhD

"Microbial genome variation in hematopoietic stem-cell transplantation patients"

Stanford University School of Medicine

Xiaowei Yan, PhD

"Spatial organization and inheritance regulation of oncogenic extrachromosomal DNA (ecDNA)"

Stanford University School of Medicine

University of California, Santa Barbara

Meghan A. Morrissey, PhD

"Nibbled to death: improving macrophage's ability to kill solid tumors by trogocytosis"

University of California, Santa Barbara

University of California, San Diego

Jinchun Wu, PhD

"Identifying cytoplasmic nucleases that shatter micronucleated chromosomes"

University of California, San Diego

Gladstone Institutes

Ronghui Zhu, PhD

"Mapping and modeling the human CD4+ T cell differentiation gene regulatory network"

Gladstone Institutes

Colorado

University of Colorado Boulder

Nicole M. Hoitsma, PhD

"Chromatin remodeler SMARCAD1 in DNA repair"

University of Colorado Boulder

Edward M. C. Courvan, PhD

"Functional analysis of post-transcriptional RNA regulation in hypoxic macrophages"

University of Colorado Boulder

Connecticut

Yale University

Hui (Vivian) Chiu, PhD

"The neuroimmune basis of fatigue"

Yale University

Yale University / Michigan State University

Jung-Shen Benny Tai, PhD

"From form to function: Cell shape, cell ordering, and gene regulation in bacterial biofilm"

Yale University / Michigan State University

Delaware

Florida

Georgia

University of Georgia

Courtney Ellison, PhD

"The regulation and function of type IV pili in Acinetobacter biofilm formation"

University of Georgia

Hawaii

Idaho

Illinois

The University of Chicago

Alexandra E. Rojek, MD

"Leveraging memory-like T-cell phenotypes to improve cellular therapies"

The University of Chicago

Northwestern University

John Devany, PhD

"Engineering next-generation T cell therapies by learning from cancer mutations"

Northwestern University

Indiana

Iowa

Kansas

Kentucky

Louisiana

Maine

Maryland

The Johns Hopkins University School of Medicine

Fyza Y. Shaikh, MD, PhD

"Defining microbiome stability and longitudinal shifts as biomarkers of tumor response to immune checkpoint inhibitors across multiple malignancies"

The Johns Hopkins University School of Medicine

Cayla E. Jewett, PhD

"Mechanisms of centriole number control in multiciliated cells"

The Johns Hopkins University School of Medicine

Marco A. Catipovic, PhD

"In vitro reconstitution of ribosome collision dependent signaling”

The Johns Hopkins University School of Medicine

National Institutes of Health

Claudia A. Rivera Cifuentes, PhD

"Endogenous retroviruses modulation of intestinal immune homeostasis and tumor development"

National Institutes of Health

Johns Hopkins University

Jamie B. Spangler, PhD

"Engineered multispecific antibody-drug conjugates as novel cancer immunotherapeutics"

Johns Hopkins University

Massachusetts

Brigham and Women's Hospital

Rebecca Pasquarelli, PhD

"Investigating novel mechanisms of tumor immune evasion"

Brigham and Women's Hospital

Humsa S. Venkatesh, PhD

"Identifying and disrupting the bioelectric circuits driving brain cancer"

Brigham and Women's Hospital

Vignesh Shanmugam, MD

"Uncovering microenvironmental dependencies in follicular lymphoma"

Brigham and Women's Hospital

Xiphias Ge Zhu, PhD

"Charting the tumor antigen landscape of breast cancer"

Brigham and Women's Hospital

Massachusetts Institute of Technology

Jane E. Lodwick, PhD

"Revealing structure and function of an anomalous bacterial secretion system throughout the host cell"

Massachusetts Institute of Technology

Phaedra C. Ghazi, PhD

"Investigating therapeutic vulnerabilities of lung cancer by tracking cellular identity"

Massachusetts Institute of Technology

Yuxuan Chen, PhD

"Genetic engineering of oncolytic viruses for pyroptosis-accelerated cancer virotherapy"

Massachusetts Institute of Technology

Isabella Evavold, PhD

"Examining bacteria as a source of tumor antigens"

Massachusetts Institute of Technology

Ian J. Roney, PhD

"Discovery and characterization of bacteriophage effectors of bacterial immune systems"

Massachusetts Institute of Technology

Expery O. Omollo, PhD

"Elucidating what determines the strength of bacterial transcription terminators"

Massachusetts Institute of Technology

Isabella Fraschilla, PhD

"Examining bacteria as a source of tumor antigens"

Massachusetts Institute of Technology

Senén D. Mendoza, PhD

"Discovery and characterization of bacterial immunity against RNA phages"

Massachusetts Institute of Technology

Patrick Woida, PhD

"Functional dissection of the bacterial-host interface during cell-to-cell spread"

Massachusetts Institute of Technology

Fangtao Chi, PhD

"Understanding how ketone body metabolites influence intestinal stemness, immune responses and tumorigenesis"

Massachusetts Institute of Technology

Dana-Farber Cancer Institute

Srivatsan Raghavan, MD, PhD

Defining and targeting transcriptional drivers of KRAS inhibitor resistance in pancreatic cancer

Dana-Farber Cancer Institute

Simone Bruno, PhD

"Optimal epigenetic therapies in triple-negative breast cancer"

Dana-Farber Cancer Institute

Lara Wahlster, MD, PhD

"Decoding mechanisms of B-acute lymphoblastic leukemia pathogenesis through the lens of genomics"

Dana-Farber Cancer Institute

Kheewoong Baek, PhD

"Expansion of the glueable and degradable targets of IMiD-CRBN"

Dana-Farber Cancer Institute

James J. Morrow, MD, PhD

"Application of single-cell approaches to investigate the developmental origin and early transformation steps of osteosarcoma"

Dana-Farber Cancer Institute

Geoffrey A. Smith, MD, PhD

"Identifying mechanisms of immune evasion in a murine model of osteosarcoma"

Dana-Farber Cancer Institute

Costanza Lo Cascio, PhD

"Investigating the neuronal regulation of radioresistance in diffuse midline gliomas"

Dana-Farber Cancer Institute

April A. Apfelbaum, PhD

"Investigation of receptor tyrosine kinase-independent mechanisms of FGFR1-mediated oncogenesis in pediatric gliomas"

Dana-Farber Cancer Institute

Lachelle D. Weeks, MD, PhD

"Predicting leukemia risk from peripheral blood smears"

Dana-Farber Cancer Institute

Megan L. Insco, MD, PhD

"Targeting cancer-associated aberrant RNA to treat metastatic melanoma"

Dana-Farber Cancer Institute

Erin M. Parry, MD, PhD

"Defining follicular lymphoma transformation: molecular basis, detection and therapeutic vulnerabilities"

Dana-Farber Cancer Institute

Rebecca L. Zon, MD

"Defining the mechanism of thrombosis in patients with multiple myeloma"

Dana-Farber Cancer Institute

Ahmed Roman, PhD

"Signal bottleneck theory for dissecting gene interactions in pancreatic cancer"

Dana-Farber Cancer Institute

Anders B. Dohlman, PhD

"Identifying the genomic basis for Fusobacterium nucleatum’s colonization of colorectal cancers"

Dana-Farber Cancer Institute

Sylvan C. Baca, MD, PhD

"Epigenetic drivers of resistance to novel therapies for bladder and kidney cancer"

Dana-Farber Cancer Institute

Nina Weichert-Leahey, MD

"Elucidating the role of KAT6A and KAT6B in the epigenetic reprogramming of neuroblastoma to enforce neuronal differentiation"

Dana-Farber Cancer Institute

Mounica Vallurupalli, MD

"Defining the mechanistic implications of SF3B1 mutations in MDS"

Dana-Farber Cancer Institute

Wallace A. Bourgeois, MD

"Characterizing mechanisms of resistance to Menin inhibitors in KMT2A-rearranged and NPM1-mutant AML"

Dana-Farber Cancer Institute

Srinivas R. Viswanathan, MD, PhD

"X marks the spot: exploring how X-chromosome alterations drive sex differences in cancer"

Dana-Farber Cancer Institute

David M. Walter, PhD

"Identifying the selective mechanism behind U2AF1 mutations in lung adenocarcinoma"

Dana-Farber Cancer Institute

Massachusetts General Hospital

Peter G. Miller, MD, PhD

"The role of RecQ helicases in premalignant hematopoiesis and myeloid neoplasia"

Massachusetts General Hospital

Charles S. Dai, MD

"Epigenetically targeting MYC through paradoxical nuclear receptor activation in hormone-dependent malignancies"

Massachusetts General Hospital

Charles H. Adelmann, PhD

"Systematic exploration of the organellar and cellular requirements of pigmentation"

Massachusetts General Hospital

Harvard Medical School

Rachel Segal Greenberg, PhD

“The function of interoceptive circuits in reproduction and cancer”

Harvard Medical School

Qinheng Zheng, PhD

“Chemical rescue of somatic mutations in cancer”

Harvard Medical School

James C. Taggart, PhD

"Mechanistic interrogation of robustness and vulnerability in a bacterial essential gene network"

Harvard Medical School

Brooke D. Huisman, PhD

"Elucidating the lineage relationships of thymic mimetic cells"

Harvard Medical School

Manuel Osorio Valeriano, PhD

"Molecular and structural basis of gene expression regulation by the nucleosome remodeling and deacetylase (NuRD) complex in human cancer"

Harvard Medical School

Dana-Farber Cancer Institute / Harvard Medical School

“Catching transcription factors for degradation via the midnolin-proteasome pathway”

Dana-Farber Cancer Institute / Harvard Medical School

Archana Krishnamoorthy, PhD

"Mechanisms of chromosome fragmentation generating chromothripsis"

Dana-Farber Cancer Institute / Harvard Medical School

The Broad Institute of MIT and Harvard

Yiyin Erin Chen, MD, PhD

"Skin commensal bacteria as a novel source of systemic antitumor immunity"

The Broad Institute of MIT and Harvard

Chaiheon Lee, PhD

"Development of haptenizing chimeras for neoantigen generation"

The Broad Institute of MIT and Harvard

Wendy Xueyi Wang, PhD

"Dissecting the molecular identity and contents of neuronal synapses using spatially resolved RNA sequencing"

The Broad Institute of MIT and Harvard

Boston Children's Hospital

"Unraveling the cellular and molecular determinants of hematopoietic aging and regeneration in stem cell transplantation"

Boston Children's Hospital

Shreoshi Sengupta, PhD

"Decoding cell-cell interactions aiding angiogenesis and immune evasion in early-stage lung cancer"

Boston Children's Hospital

Saket Rahul Bagde, PhD

"Integrin a6ß4 in hemidesmosome dynamics: structural and functional insights for tissue homeostasis, organoid growth, and cancer"

Boston Children's Hospital

Longyue Lily Cao, MD, PhD

"Using hyperactive dendritic cells to generate improved cancer vaccines"

Boston Children's Hospital

Ryan A. Flynn, MD, PhD

"Tools to target novel cell surface ligands in cancer"

Boston Children's Hospital

Harvard University

Antonio J. LaPorte, PhD

"A general platform for preparation and study of 3O-sulfated sugars"

Harvard University

Alon Chappleboim, PhD

"Uncovering signaling mechanisms in somitogenesis through high-throughput genetic screens in robust human organoids"

Harvard University

Whitehead Institute for Biomedical Research

"An integrated imaging- and sequencing-based spatial-omic method to study tumor evolution"

Whitehead Institute for Biomedical Research

Ryan Y. Muller, PhD

"Elucidating PABPC1 sequence preferences and determining how these preferences shape gene regulation"

Whitehead Institute for Biomedical Research

Henry R. Kilgore, PhD

"Subcellular pharmacokinetics"

Whitehead Institute for Biomedical Research

Harvard T.H. Chan School of Public Health

"Targeting mitochondrial transporters in cancer"

Harvard T.H. Chan School of Public Health

Madi Y. Cissé, PhD

"Integration on oncogenic signaling and nutrient sensing by mTOR in tumors"

Harvard T.H. Chan School of Public Health

Michigan

University of Michigan, Ann Arbor

John R. Prensner, MD, PhD

"Therapeutic opportunities and biological mechanisms for protein-RNA dyssynchrony in medulloblastoma"

University of Michigan, Ann Arbor

Van Andel Institute

McLane Watson, PhD

"Understanding CD8 T cell epigenetic changes fueled by S-adenosylmethionine metabolism for improved adoptive cell therapy"

Van Andel Institute

University of Michigan

Phillip L. Palmbos, MD, PhD

"Targeting TRIM29 to reverse immune checkpoint inhibitor resistance in bladder cancer"

University of Michigan

Minnesota

Mississippi

Missouri

Washington University

Mary M. Mullen, MD

"COPS5 as a novel therapeutic target in platinum-resistant ovarian cancer"

Washington University

Nathan Singh, MD

"Tailored cellular engineering to overcome costimulation-driven CAR T cell dysfunction"

Washington University

Washington University School of Medicine

Kelly L. Bolton, MD, PhD

"The use of ivosidenib in IDH1-mutated clonal cytopenia of undetermined significance"

Washington University School of Medicine

Montana

Nebraska

Nevada

New Hampshire

Geisel School of Medicine at Dartmouth

Leslie A. Day, PhD

"From tools to tumors: building genetic systems to determine Prevotella's role in cancer"

Geisel School of Medicine at Dartmouth

St. Jude Children's Research Hospital

Esteban A. Orellana Vinueza, PhD

"tRNA dysregulation and cancer"

St. Jude Children's Research Hospital

New Jersey

Rutgers University

Natasha O'Brown, PhD

"Leveraging zebrafish models to overcome blood-brain barrier in glioblastoma treatment"

Rutgers University

Princeton University

Hasreet K. Gill, PhD

"Defining mechanisms by which quorum sensing and 3D morphogenesis interact in space and time to drive Vibrio cholerae pellicle maturation"

Princeton University

Cheng Yang, PhD

"Developing an activity-based sensing probe for selective monitoring ammonia in cancer"

Princeton University

Jeremy A. Owen, PhD

"The biophysics of substrate recognition in chromatin remodeling"

Princeton University

Juner Zhang, PhD

"Developing tools to decode endogenous protein monoaminylation"

Princeton University

Carolina Trenado-Yuste, PhD

"Screening migratory modes and drug delivery schedules in 3D spheroids of triple-negative breast cancer cells"

Princeton University

Titas Sengupta, PhD

"Investigating bacterial small RNA-mediated regulation of host behavior"

Princeton University

Grace E. Johnson, PhD

"Defining quorum-sensing signaling patterns and their effects on gene expression and morphology in V. cholerae biofilms at the single-cell and community levels"

Princeton University

New Mexico

New York

Memorial Sloan Kettering Cancer Center

Subyeta Chowdhury

Memorial Sloan Kettering Cancer Center

Denis Torre, PhD

"Dissecting dynamic cellular responses to genetic perturbations using time-resolved single-cell CRISPR screens"

Memorial Sloan Kettering Cancer Center

Paul C. Klauser, PhD

"Generative artificial intelligence enabling next-generation radiopharmaceuticals"

Memorial Sloan Kettering Cancer Center

Tamar Kavlashvili, PhD

"Developing Tools to Mechanistically Investigate the mtDNA 'Common Deletion'"

Memorial Sloan Kettering Cancer Center

"Understanding the role of R-loops in cancer at the single cell level"

Memorial Sloan Kettering Cancer Center

Justin Perry, PhD

"Tumor-macrophage metabolic symbiosis as a driver of disease progression and therapeutic resistance"

Memorial Sloan Kettering Cancer Center

Ariën Schiepers, PhD

"Regulatory T cells in health and disease: from Foxp3 dependence to resilience and back again"

Memorial Sloan Kettering Cancer Center

Antonio Cuevas-Navarro, PhD

"Elucidating mechanisms that reverse the detrimental effect of RAS mutations in cancer"

Memorial Sloan Kettering Cancer Center

Nalin Ratnayeke, PhD

"Dissecting heterogeneous cellular responses to oncogenic KRAS inhibition in pancreatic adenocarcinoma"

Memorial Sloan Kettering Cancer Center

Michael V. Gormally, MD, PhD

"Immunologic targeting of 'undruggable' TP53 hotspot mutations through T cell receptor gene therapy"

Memorial Sloan Kettering Cancer Center

"Origin and evolution of long-lived CAR T cells in patients with hematologic malignancies"

Memorial Sloan Kettering Cancer Center

Santosha A. Vardhana, MD, PhD

"Overcoming metabolic suppression of anti-tumor immunity in gastric cancer"

Memorial Sloan Kettering Cancer Center

Junhong Choi, PhD

"Uncovering cellular development in cancer through precise genome editing"

Memorial Sloan Kettering Cancer Center

Icahn School of Medicine at Mount Sinai

Léa Montégut, PhD

"Targeting age-driven myeloid dysfunction in cancer: unraveling the immunomodulatory and metabolic contributions of GLP-1R agonists"

Icahn School of Medicine at Mount Sinai

Daniel J. Puleston, PhD

"A new platform to study cancer biology and therapy in humans"

Icahn School of Medicine at Mount Sinai

Andrew L. Ji, MD

"Dissecting spatial crosstalk in squamous cell carcinoma arising in organ transplant recipients"

Icahn School of Medicine at Mount Sinai

New York Genome Center

Aaron Zweig, PhD

"Geometric modeling of perturbed gene regulation dynamics across time and space"

New York Genome Center

Isabella N. Grabski, PhD

"A probabilistic framework for deconvolving causal mechanisms of cancer therapeutics with genetic perturbation screens"

New York Genome Center

Oriana Miltiadous, MD

"Investigating the role and therapeutic potential of microbiome and bile acids in immune recovery and graft-versus-host disease in pediatric allogeneic transplantation"

New York University School of Medicine

Mark Yarmarkovich, PhD

"Unveiling the tumor antigenome through immune intelligence"

New York University School of Medicine

The Rockefeller University

Wenzhi Song, PhD

"Neuroimmune: cancer stem cell interactions in the tumor microenvironment"

The Rockefeller University

Nicole M. Cruz, MD

"Understanding the role of KMT2D in MLL-AF9 acute myeloid leukemia"

The Rockefeller University

Catherine A. Freije, PhD

"Investigating the role of fitness and host pressure in shaping hepatitis B diversity"

The Rockefeller University

Columbia University

James Swann, VetMB, DPhil

"Emergency myelopoiesis pathways as common drivers of clonal dominance and disease progression in acute myeloid leukemia"

Columbia University

Mingjian Du, PhD

"The gut-brain axis mediating overnutrition"

Columbia University

Aaron D. Viny, MD

"Epigenetic coupling of DNA methylation and chromatin structure on leukemic transformation and therapeutic response"

Columbia University

Memorial Sloan Kettering Institute for Cancer Research

Zeda Zhang, PhD

"Decode the senescent cell surface in vivo and develop cell therapies for senescence-related diseases"

Memorial Sloan Kettering Institute for Cancer Research

Rico C. Ardy, PhD

"An atlas of fibroblast cell states in health and disease through functional genomics"

Memorial Sloan Kettering Institute for Cancer Research

North Carolina

Duke University School of Medicine

Elizabeth R. Hughes, PhD

"Mechanisms of microbial modulation of cancer immunotherapy"

Duke University School of Medicine

North Dakota

Ohio

Cincinnati Children's Hospital Medical Center

Annabelle J. Anandappa, MD

"The role of inflammatory signaling in the pathogenesis and therapeutic targeting of RAS-mutated AML"

Cincinnati Children's Hospital Medical Center

Oklahoma

Oregon

Oregon Health & Science University

Tanaya Shree, MD, PhD

"Unraveling resistance to bispecific T-cell engagers"

Oregon Health & Science University

Pennsylvania

University of Pennsylvania

Sydney M. Shaffer, MD, PhD

"Spatially resolved cellular competition in oncogenesis"

University of Pennsylvania

Rahul S. Bhansali, MD

"Investigating chromatin architectural dynamics mediated by LDB1 in T-cell acute lymphoblastic leukemia"

University of Pennsylvania

Nicholas P. Lesner, PhD

"Hepatic urea cycle function in NASH-induced HCC progression"

University of Pennsylvania

Christopher Noetzel, PhD

"How do eukaryotic cells count cell cycles? Intrinsic regulation of quantized asexual replication cycles and commitment to sexual differentiation in the protozoan parasite Cryptosporidium parvum"

University of Pennsylvania

Rebecca S. Moore, PhD

"Investigation of the role of peripheral secreted molecules on sleep and circadian rhythms"

University of Pennsylvania

Catherine Triandafillou, PhD

"Illuminating error correction strategies in early development"

University of Pennsylvania

Alexander C. Huang, MD

"Shared antigen and neoantigen-specific T cells in checkpoint blockade efficacy and toxicity"

University of Pennsylvania

University of Pennsylvania, Perelman School of Medicine

Sangin Kim, PhD

"ATM kinase orchestrates transcription silencing and anti-tumor immune responses"

University of Pennsylvania, Perelman School of Medicine

University of Pittsburgh

Benjamin A. Nacev, MD, PhD

"Understanding and targeting chromatin reorganization in ATRX deficient sarcomas"

University of Pittsburgh

Rhode Island

South Carolina

South Dakota

Tennessee

St. Jude Children's Research Hospital

Tuyu Zheng, PhD

"Functional characterization of tumor neuronal networks that drive ependymoma"

St. Jude Children's Research Hospital

Vanderbilt University Medical Center

Sarah L. Price, PhD

"Targeting Clostridioides difficile biofilm dynamics to combat recurrent infections"

Vanderbilt University Medical Center

Texas

University of Texas Southwestern Medical Center

University of Texas Southwestern Medical Center

Fangyu Liu, PhD

"Targeting membrane enzymes for next-generation precision medicine against cancer"

University of Texas Southwestern Medical Center

The University of Chicago

Ruoyu Wang, PhD

"Single-molecule sequence models to decode regulatory genome in cancers"

The University of Chicago

The University of Texas MD Anderson Cancer Center

Pavan Bachireddy, MD

"Immune evasive circuits that define MRD progression in myelodysplastic syndrome"

The University of Texas MD Anderson Cancer Center

Utah

University of Utah

Parker J. Nichols, PhD

"Elucidating the mechanism of inosine-dependent inhibition of RIG-I-like receptor filamentation and interferon signaling"

University of Utah

Vermont

Virginia

Washington

Fred Hutchinson Cancer Research Center

Fred Hutchinson Cancer Research Center

"Deciphering clonal competition between oncogenic mutant and normal cells and its effect on cancer initiation"

Fred Hutchinson Cancer Research Center

Ian Blumenthal, PhD

"Addressing antigen heterogeneity in pediatric gliomas with tumor-assimilating multispecific immune cell engagers"

University of Washington

Wei (Will) Chen, PhD

"Decoding the transcription code: de novo protein design for precise gene regulation"

University of Washington

Nicholas C. Lammers, PhD

"A computational platform for predicting whole-embryo morphologies from single-cell transcriptomes"

University of Washington

Erik Van Dis, PhD

"Investigating innate immune activation in the autoimmune pancreas"

University of Washington

West Virginia

Wisconsin

Wyoming