Cutting-edge Research by the Best and Brightest

Damon Runyon cancer researchers work in technologically advanced labs and leading hospitals across the country.

Select a highlighted state to learn more about the scientists
and projects that Damon Runyon is currently funding.

Scientists by State

California Institute of Technology

Ariana Peck, PhD
"Expanding the reach of structure determination with nanocrystal tomography" with Grant J. Jensen, PhD

City of Hope

Mingye Feng, PhD
"Macrophage-mediated immunosurveillance in metastasis"

Stanford University

Christopher J. Cambier, PhD
"In vivo characterization of mycobacterial cording" with Carolyn Bertozzi, PhD
Jennifer L. Caswell-Jin, MD
"Breast cancer evolution and resistance in response to HER2-targeted therapy" with Christina N. Curtis, PhD, and Allison W. Kurian, MD
Scott J. Dixon, PhD
"Exploring the role of reductive stress in promoting cancer cell death"
Kelsie A. Eichel, PhD
"Mechanisms of polarized membrane protein trafficking" with Kang Shen, PhD
Ryan A. Flynn, MD, PhD
"The interplay between cellular metabolism and RNA homeostasis in disease" with Carolyn R. Bertozzi, PhD
Christina L. Hueschen, PhD
"Molecular basis and regulation of apicomplexan parasite motility" with Alex Dunn, PhD
Victoria Hung, PhD
"Defining the post-translational landscape of ribosomes in control of gene regulation and cell fate" with Maria Barna, PhD
John C. Janetzko, PhD
"A biophysical approach to studying GRK-GPCR complexes" with Brian K. Kobilka, MD
Kathrin Leppek, PhD
"Mechanistic characterization of 5’UTR RNA elements that confer translational specificity to shape vertebrate embryonic development" with Maria Barna, PhD
Chuan Li, PhD
"Quantifying epistasis between tumor suppressor genes and revealing the underlying expression profiles at the single-cell level in murine lung adenocarcinoma" with Dmitri Petrov, PhD
Fangfei Qu, PhD
"Decoding the molecular and cellular mechanisms underlying the growth of brain metastases" with Julien Sage, PhD
Kavita Y. Sarin, MD, PhD
"Genetic contributions and novel therapies for individuals with frequent basal cell cancer" with Jean Y. Tang, MD, PhD, and Anthony E. Oro, MD, PhD
Jianjin Shi, PhD
"Biochemical and genetic dissection of axon degeneration" with Marc Tessier-Lavigne, PhD
Shaogeng (Steven) Tang, PhD
"Toward small-molecule inhibitors against human immune checkpoint PD-1" with Peter S. Kim, PhD
Kathryn R. Taylor, PhD
"The effect of neuronal activity on pediatric glioma invasion" with Michelle L. Monje, MD, PhD
Albert G. Tsai, MD, PhD
"Diagnosis of hematologic malignancies from paucicellular aspirate material using highly multiplexed single cell analysis" with Sean Bendall, PhD
Peng Wu, MD, PhD
"Understanding and modulating aberrant differentiation in Hepatoblastoma"  with Roeland Nusse, PhD
Jing Lin Xie, PhD
"Remembering the past: epigenetic mechanisms of cancer drug resistance" with Daniel F. Jarosz, PhD
Leeat Yankielowicz-Keren, PhD
"Studying the tumor immune microenvironment in breast cancer using a novel multiplexed imaging platform" with Michael R. Angelo, MD, PhD, and Edgar G. Engleman, PhD

Stanford University School of Medicine

Christopher P. Lapointe, PhD
"Regulatory roles of the 3' untranslated region in human translation" with Joseph Puglisi, PhD

The Salk Institute for Biological Studies

Corina E. Antal, PhD
"Stromal reprogramming as a therapeutic approach in pancreatic cancer" with Ronald M. Evans, PhD
Hokyung K. Chung, PhD
"Next generation adoptive cell therapy: SMARTER T cells for enhanced and durable anti-tumor immunity" with Susan Kaech, PhD
Thomas H. Mann, PhD
"Calcium signaling and the molecular clock of T cell exhaustion" with Susan M. Kaech, PhD

The Scripps Research Institute

Marsha M. Hirschi, PhD
"Molecular engineering of an optically controlled glutamate receptor" with Gabriel C. Lander, PhD
Xiaoyu Zhang, PhD
"Discovery of chemical probes that support targeted protein degradation in human cancer" with Benjamin F. Cravatt, PhD

University of California San Francisco

Adam J. Stevens, PhD
"Synthetic adhesion molecules: redirecting cell infiltration and organization" with Wendell A. Lim, PhD

University of California, Berkeley

Gina V. Caldas, PhD
"Analysis of CSR- function in C. elegans embryonic cell division" with Abby F. Dernburg, PhD
Allison Didychuk, PhD
"Viral mimics of host transcription factors in oncogenic herpesviruses" with Britt Glaunsinger, PhD
Stephanie Gates, PhD
"Decoding the ubiquitin receptor recognition mechanism of the 26S proteasome" with Andreas Martin, PhD
Jamie Lahvic, PhD
"Uncovering cell non-autonomous mechanisms of tumor suppression" with Iswar Hariharan, MBBS, PhD
Andrew C. Murley, PhD
"Cell non-autonomous communication of ER stress resistance" with Andrew G. Dillin, PhD
Roberto Zoncu, PhD
"Identifying and disabling organelle circuits that fuel cancer cell metabolism"

University of California, Los Angeles

Christina M. Termini, PhD
"Proteoglycan remodeling of the bone marrow niche regulates hematopoietic stem cell regeneration" with John P. Chute, MD

University of California, San Diego

Richard W. Baker, PhD
"Understanding the mechanism of SWI/SNF-mediated chromatin remodeling and its misregulation in cancer" with Andres E. Leschziner, PhD
Janice M. Reimer, PhD
"Regulation of nucleosome remodelers" with Andres Leschziner, PhD
Alistair B. Russell, PhD
"Impact of heterogeneity on the cellular recognition of influenza"

University of California, San Francisco

Collin M. Blakely, MD, PhD
"Mechanisms of incomplete response and primary resistance to osimertinib in EGFR-mutant lung cancer" with Trever G. Bivona, MD, PhD
Vladislav Belyy, PhD
"Mapping the unfolded protein response signaling network with optogenetic actuators" with Peter Walter, PhD
Julia C. Carnevale, MD
"Developing new therapeutic approaches for pancreatic cancer with homologous recombination repair defects" with Alan Ashworth, PhD
Kyle G. Daniels, PhD
"Controlling T cell signaling and fate choice using synthetic receptors" with Wendell Lim, PhD
Jeffrey A. Hussmann, PhD
"Genome-wide measurement of ribosome spacing on individual transcripts" with Carol Gross, PhD
Brian J. Laidlaw, PhD
"Role of EBI2 in the regulation of lymphocyte migration during viral infection and cancer" with Jason Cyster, PhD
Kara L. McKinley, PhD
"Mechanisms and functions of cellular rearrangements in epithelia" with Ronald D. Vale, PhD
Trang Nguyen, PhD
"Bypassing the unresponsiveness of T cell anergy and exhaustion" with Arthur Weiss, MD, PhD
Thomas M. Norman, PhD
"Identifying the stochastic determinants of drug resistance"
Rushika M. Perera, PhD
"Mechanisms of cellular transformation at the single organelle level"
Zulekha A. Qadeer, PhD
"Targeting TGFb pathway dependencies in Group 3 Medulloblastoma"  with William A. Weiss, MD, PhD
Jessica Sheu-Gruttadauria, PhD
"Probing the dynamic organizational network of membraneless organelles through systems-level analysis and imaging" with Ronald D. Vale, PhD
Sukrit Silas, PhD
"Discovery and characterization of virally-encoded translation factors" with Jonathan S. Weissman, PhD, and Carol A. Gross, PhD
Digvijay Singh, PhD
"Cryo-electron tomography of phase-separated transcription factories in situ" with Elizabeth Villa, PhD
Catherine C. Smith, MD
"Defining structure, function and therapeutic impact of oncogenic FLT3 mutations" with Neil P. Shah, MD, PhD
Peter J. Turnbaugh, PhD
"The gut microbiome: an unexpected contributor to cancer drug resistance"
Linda T. Vo, PhD
"Off-the-shelf T cells from human pluripotent stem cells with precise tumor recognition using combinatorial antigen-sensing circuits" with Jeff A. Bluestone, PhD
Lan Wang, PhD
"Conferring organelle-specificity to tail-anchored proteins" with Peter Walter, PhD
Yichen Xu, PhD
"Elucidating a non-classical role of ER in gene expression and breast cancer progression" with Davide Ruggero, PhD
Dian Yang, PhD
"Dissecting intratumoral heterogeneity and hierarchy at single cell resolution" with Jonathan S. Weissman, PhD, and Trever G. Bivona, MD, PhD
Ziyang Zhang, PhD
"Controlling the activity of bispecific T cell engagers with a chemically cleavable molecular switch" with Kevan M. Shokat, PhD
Xin Zhou, PhD
"Understanding and perturbing protein post-translational modifications in cancer and autoimmune diseases" with James A. Wells, PhD

Yale University

Esen Sefik, PhD
"The effect of microbes, diet on the intestinal immune system in the context of obesity" with Richard A. Flavell, PhD
Seyed Fakhreddin Torabi, PhD
"Evolution of triplex-forming RNAs from random sequences: a search for additional MALAT1-like triplex motifs" with Joan Steitz, PhD

Northwestern University

Jaehyuk Choi, MD, PhD
"Development of novel therapeutic strategies for aggressive CTCL subtypes" with Stephen D. Miller, PhD, and Joan Guitart, MD

The University of Chicago

Michael W. Drazer, MD
"Defining leukomogenic mechanisms in hereditary hematologic malignancies" with Lucy A. Godley, MD, PhD
Sigrid Nachtergaele, PhD
"The dynamic N1-methyladenosine methylome in eukaryotic mRNA"

University of Illinois, Urbana-Champaign

Daniel J. Blair, PhD
"An automated small molecule synthesizer for the discovery of new anti-cancer agents" with Martin D. Burke, MD, PhD

National Institutes of Health

Danfeng Cai, PhD
"Protein crowding and protein folding landscapes as predictors of healthy and diseased cell states" with Jennifer Lippincott-Schwartz, PhD
Warakorn Kulalert, PhD
"Characterization of the microbiota-mediated cutaneous neuroimmune interface and its impacts on tumorgenesis and cancer therapy" with Yasmine Belkaid, PhD

The Johns Hopkins University

Daniel H. Goldman, PhD
"Investigating translation-mediated quality control using live-cell single-mRNA imaging" with Rachel Green, PhD
Michael A. Koldobskiy, MD, PhD
"DNA methylation stochasticity in pediatric pre-B cell acute lymphoblastic leukemia" with Andrew P. Feinberg, MD
Cara A. Rabik, MD, PhD
"Determination of the role of WT1 in hematopoiesis and leukemogenesis" with Patrick A. Brown, MD

The Johns Hopkins University School of Medicine

Xintong Dong, PhD
"Investigating ligand-receptor interactions between defensins and mrgprs in cutaneous inflammation and wound healing" with Xinzhong Dong, PhD
Evan J. Worden, PhD
"The mechanistic basis of crosstalk between histone H2B ubiquitylation and H3K79 methylation" with Cynthia Wolberger, PhD
Boris Zinshteyn, PhD
"Mechanisms of splicing-independent nonsense-mediated mRNA decay" with Rachel Green, PhD

Boston Children's Hospital

Liudmila Andreeva, PhD
"Making an inflammasome: Structural and biochemical elucidation of NLRP3 inflammasome activation" with Hao Wu, PhD
Megan Insco, MD, PhD
"Investigating transcriptional cyclin dependent kinases as novel melanoma drug targets" with Len Zon, MD
Aaron L. Moye, PhD
"Role of Lgr6-expressing Mesenchymal cells in lung cancer initiation and progression" with Carla Kim, PhD
Esteban A. Orellana Vinueza, PhD
"Role of METTL1-WDR4 tRNA methyltransferase complex in cancer" with Richard I. Gregory, PhD
Yuxiang Zhang, PhD
"Mechanisms that promote DNA double strand break clusters in brain and liver" with Frederick W. Alt, PhD
Ge Zheng, PhD
"Novel approaches to targeting zinc-finger domain of the transcription repressor BCL11A" with Stuart Orkin, MD

Brigham and Women's Hospital

Gabriel K. Griffin, MD
"Enhancing cancer immunotherapy through epigenetic modulation of the repetitive genome" with Bradley E. Bernstein, MD, PhD, and Arlene H. Sharpe, MD, PhD
Emma Watson, PhD
"Metabolic stress response: Exploring transcript-level regulation of metabolic feedback" with Stephen Elledge, PhD

Dana-Farber Cancer Institute

Edmond M. Chan, MD
"Validating a novel synthetic lethal target for microsatellite unstable cancers" with Adam J. Bass, MD
Phillip A. Dumesic, MD, PhD
"Identification of muscle-secreted factors responsible for local and systemic effects of exercise" with Bruce M. Spiegelman, PhD
Adam D. Durbin, MD, PhD
"Interrogation of neuroblastoma dependencies and non-coding RNAs on the core-regulatory circuitry for therapeutic inhibition" with A. Thomas Look, MD
Eric S. Fischer, PhD
"Novel mechanisms for small molecule induced targeted degradation of RRM family proteins"
Christopher J. Gibson, MD
"Elucidating the connection between clonal hematopoiesis and lymphoma in humans" with Benjamin L. Ebert, MD, PhD
Lillian M. Guenther, MD
"Investigation of CITED2 as a novel dependency in Ewing sarcoma" with Kimberly Stegmaier, MD
Tikvah K. Hayes, PhD
"Systematic genomic and functional analysis of small cell lung cancer" with Matthew L. Meyerson, MD, PhD
Whitney Johnson, PhD
"Using organoid cancer models to identify genome catastrophe mechanisms" with David Pellman, MD
Loretta S. Li, MD
"Mechanisms of disease and resistance in CRLF2-rearranged B-cell acute lymphoblastic leukemia" with David M. Weinstock, MD
Joseph D. Mancias, MD, PhD
“Identifying the pancreatic tumor MHC-I ligandome in response to ionizing radiation for combination radiation-immunotherapy”
Jasper E. Neggers, PhD
"Validation of VPS4A as a synthetic lethal target in cancers with VPS4B loss on chromosome 18q" with Andrew J. Aguirre, MD, PhD, and Todd R. Golub, MD
Sarah Naomi Olsen, PhD
"Targeted degradation of the MLL-AF9 fusion oncoprotein in acute myeloid leukemia" with Scott A. Armstrong, MD, PhD
Matthew G. Oser, MD, PhD
"Targeting neuroendocrine differentiation as a novel therapeutic strategy for small cell lung cancer" with William G. Kaelin, Jr., MD
Geoffrey R. Oxnard, MD
"Clinical translation of plasma cell-free DNA (cfDNA) genotyping technologies for NSCLC care" with Pasi A. Janne, MD, PhD
Harshabad Singh, MBBS
"Cellular origins of Barrett’s esophagus and its role in development of adenocarcinoma" with Ramesh A. Shivdasani, MD, PhD
Eliezer M. Van Allen, MD
"Dissecting response to conventional and emerging DNA damage and repair therapies" with Geoffrey I. Shapiro, MD, PhD
Eric Wang, PhD
"Enhancing anti-tumor immunity via pharmacological inhibition of kinases" with Nathanael Gray, PhD

Harvard Medical School

Justin A. Bosch, PhD
"Characterizing novel molecules and mechanisms that mediate cell-cell communication" with Norbert Perrimon, PhD
Amelia N. Chang, PhD
"The role of activity-regulated gene expression in human brain evolution" with Michael E. Greenberg, PhD
Anne E. Dodson, PhD
"Transgenerational inheritance of structure-based infections" with Scott G. Kennedy, PhD
Yuan Gao, PhD
"Mechanism of protein import into peroxisomes" with Tom A. Rapoport, PhD
Ivana Gasic, Dr.Sc.
"Molecular elucidation of the interphase microtubule integrity response (MIR)" with Timothy Mitchison, PhD
Zhejian Ji, PhD
"Function of the Cdc48 ATPase in protein degradation" with Tom A. Rapoport, PhD
Lucy Liu, PhD
"The fat-brain axis: identifying the roles of adipokine signaling in nervous system function" with Norbert Perrimon, PhD
Nagarajan Nandagopal, PhD
"Signal integration by bHLH circuits to enable cell fate decisions" with Galit Lahav, PhD, and Sean Megason, PhD
Natasha M. O'Brown, PhD
"Molecular and cellular mechanisms of transcytosis regulation in blood-brain barrier function" with Sean G. Megason, PhD, and Chenghua Gu, PhD
Sarah J. Pfau, PhD
"Investigating the molecular determinants of blood-brain barrier heterogeneity" with Chenghua Gu, PhD
Maxim Pimkin, MD, PhD
"Divergent core transcriptional circuitries highlight context-specific vulnerabilities in AML" with Stuart Orkin, MD
Deepshika Ramanan, PhD
"Identifying functions of regulatory T cell subsets in intestinal inflammation and colorectal cancer" with Christophe Benoist, MD, PhD
Justin L. Sparks, PhD
"Replicative helicase bypass of bulky DNA lesions"
Benjamin M. Stinson, PhD
"Mechanism of DNA processing during non-homologous end joining" with Johannes C. Walter, PhD, and Joseph L. Loparo, PhD
Jonathan G. Van Vranken
"Systematic identification of metabolite-protein interactions in human cells" with Steven Gygi
Chuchu Zhang, PhD
"Molecular dissection of the Area Postrema and its role in nausea" with Stephen D. Liberles, PhD

Harvard T.H. Chan School of Public Health

Jeeyun Chung, PhD
"Unraveling the cellular mechanism of lipid droplet biogenesis" with Tobias C. Walther, PhD, and Robert V. Farese Jr. MD

Harvard University

Philip B. Abitua, PhD
"Developmental mechanisms of killifish cell dispersion and aggregation" with Alexander Schier, PhD
Grace E. Kenney, PhD
"Two enzymatic routes towards diazo biosynthesis in cytotoxic natural products" with Emily P. Balskus, PhD
Thomas R. LaBar, PhD
"Elucidating the mechanisms of cellular evolution with experimental evolution" with Andrew W. Murray, PhD
Monica E. McCallum, PhD
"Understanding alanosine biosynthesis to discover new cancer chemotherapeutics" with Emily P. Balskus, PhD
Christopher Wilson, PhD
"Development of a programmable writer and eraser of m6A RNA methylation" with David R. Liu, PhD

Koch Institute for Biomedical Research

Alexander M. Jaeger, PhD
"Targeting protein folding mechanisms to stimulate anti-tumor immune responses" with Tyler E. Jacks, PhD
Evan C. Lien, PhD
"Impact of diet on tumor metabolism and progression" with Matthew G. Vander Heiden, MD, PhD

Massachusetts Eye and Ear Infirmary

Mark G. Shrime, MD, MPH, PhD
"Cash transfers for cancer surgery in West Africa: their health and economic consequences" with John G. Meara, MD, DMD, MBA

Massachusetts General Hospital

Liron Bar-Peled, PhD
"Identification of cysteine liabilities in NRF2-driven cancers"
Priscilla K. Brastianos, MD
"Investigation of novel targeted therapeutic approaches for brain metastases" with Keith T. Flaherty, MD and Tracy T. Batchelor, MD
Marcela V. Maus, MD, PhD
"Next-generation CAR T cells for EGFRvIII-positive glioblastoma"
Jan P. Schuemann, PhD
“Using extreme dose rates to protect healthy tissue in proton radiation therapy”
Iva Tchasovnikarova, PhD
"Deciphering the role of chromatin remodeling in epigenetic repression by the HUSH complex" with Robert Kingston, PhD
Alexandra-Chloé Villani, PhD
"Deciphering the Achilles' heel of cancer immunotherapy"
Kurt J. Warnhoff, PhD
"Molybdenum cofactor biosynthetic enzymes modulate miRNA biology and development" with Gary B. Ruvkun, PhD
Jingyi Wu, PhD
"Epigenetic clonal evolution in gliomas" with Bradley Bernstein, MD, PhD

Massachusetts Institute of Technology

Lindsay M. LaFave, PhD
"Investigating epigenetic mechanisms of transformation in SWI/SNF-mutant non-small cell lung cancer" with Tyler Jacks, PhD
Jose M. Ordovas-Montanes, PhD
"Single-cell genomic approaches for tracing the contribution of inflammation to human colon cancer" with Alex Shalek, PhD
Sharanya Sivanand, PhD
"Understanding metabolic heterogeneity in primary and metastatic tumors" with Matthew G. Vander Heiden, MD, PhD
Peter M. K. Westcott, PhD
"Exploiting endogenous mutational processes in cancer to enhance response to immunotherapy" with Tyler Jacks, PhD

University of Massachusetts Medical School

Sakiko Suzuki, MD
"Inflammatory cell death pathways in Myelodysplastic Syndromes" with Michelle A. Kelliher, PhD, and Peter E. Newburger, MD

Whitehead Institute for Biomedical Research

Laura Blanton, PhD
"The impact of sex chromosome constitution on immune cell gene expression and function" with David C. Page, MD
Elizabeth A. Costa, PhD
"Exploring the cell adhesion landscape through host-pathogen interactions" with Sebastian Lourido, PhD
Daniel H. Lin, PhD
"Global influence of mRNA conformation on eukaryotic translational regulation" with David P. Bartel, PhD
Alexandra Nguyen, PhD
"Defining the cell type specific cell division requirements in acute myeloid leukemias" with Iain M. Cheeseman, PhD
Benjamin R. Sabari, PhD
"Biomolecular condensates in normal and diseased gene regulation" with Richard A. Young, PhD

Michigan State University

Jens C. Schmidt, PhD
"Single-molecule analysis of telomerase recruitment to telomeres"

University of Michigan

Ryan D. Baldridge, PhD
"Investigating the mechanism of retro-translocation by ERAD"

Princeton University

Caroline Bartman, PhD
"Systems analysis of in vivo tumor and stromal cell metabolism in pancreatic ductal adenocarcinoma" with Joshua Rabinowitz, MD, PhD
Andrew A. Bridges, PhD
"Bacterial cell fates: The role of quorum sensing in biofilm patterning" with Bonnie L. Bassler, PhD
Antony J. Burton, PhD
"Sculpting chromatin architecture in live cells using protein chemistry" with Tom W. Muir, PhD

Albert Einstein College of Medicine

Srinjoy Chakraborti, PhD
"Mining pHLA and T cell receptors (TCR) specificities by phage display for de novo TCR engineering and personalized cancer therapy" with Jonathan R. Lai, PhD

Cold Spring Harbor Laboratory

Jason M. Sheltzer, PhD
“Are cancers addicted to aneuploidy?”

Columbia University

Jessie A. Brown, PhD
"Master regulators of drug resistance in relapsed acute lymphoblastic leukemia"  with Adolfo A. Ferrando, MD, PhD
J. Brooks Crickard, PhD
"Visualizing the strand invasion during homologous recombination on the single molecule level" with Eric C. Greene, PhD
Arnold S. Han, MD, PhD
"Precision T cell receptor-based cancer therapies"
Chao Lu, PhD
"Chromatin dysregulation as driver of oncogenesis"
Neel H. Shah, PhD
"Identifying divergent mechanisms of oncogenicity in tyrosine kinases"

Columbia-Presbyterian Medical Center

Marissa Rashkovan, PhD
"Targeting metabolic vulnerabilities in ETP-ALL" with Adolfo A. Ferrando, MD, PhD

Cornell University

Sudeep Banjade, PhD
"Division of labor in ESCRT-III proteins during polymer assembly and membrane remodeling" with Scott Emr, PhD

Icahn School of Medicine at Mount Sinai

Amaia Lujambio, PhD
"Overcoming resistance to anti-PD1 immunotherapy in hepatocellular carcinoma"

Memorial Sloan Kettering Cancer Center

Vinod P. Balachandran, MD
"Defining the evolutionary dynamics and antigen potential of neoantigens for human pancreatic cancer immunotherapy" with Steven D. Leach, MD, and Jedd D. Wolchok, MD, PhD
Harihar Basnet, PhD
"Identifying determinants of latency in brain metastatic breast cancer cells" with Joan Massague, PhD
Adrienne A. Boire, MD, PhD
"Molecular determinants of leptomeningeal metastasis: a translational approach" with Joan Massagué, PhD
Robert L. Bowman, PhD
"Interrogating the subclonal architecture and functional contributions of mutation order in FLT3-ITD mutant AML" with Ross L. Levine, MD
Andrew J. Dunbar, MD
"Interrogating functional contribution of JAK2V617F in the maintenance of myeloproliferative neoplasms" with Ross L. Levine, MD
Karuna Ganesh, MD, PhD
"Leveraging patient-derived organoid models to define the molecular determinants of metastatic regeneration" with Joan Massagué, PhD
Matthew D. Hellmann, MD
"Defining intratumoral and peripheral mechanisms mediating initiation of response, durability, and resistance to PD-1 blockade to inform rational immunotherapeutic development in NSCLC" with Charles M. Rudin, MD, PhD, and Jedd D. Wolchok, MD, PhD
Andrew M. Intlekofer, MD, PhD
"Metabolic coupling of the hypoxic niche to stemness" with Ross L. Levine, MD
Christopher A. Klebanoff, MD
"Clinical development of next-generation T cell receptor (TCR)-based adoptive immunotherapies for the treatment of patients with common epithelial malignancies" with Michel Sadelain, MD, PhD, and Larry Norton, MD
Piro Lito, MD, PhD
"Modeling the evolution of resistance to ERK signaling inhibitors at the single cell level" with Neal X. Rosen, MD, PhD, and Charles M. Rudin, MD, PhD
Melody Smith, MD
"CD19 targeted donor T cells improve graft versus tumor activity and reduce graft versus host disease" with Marcel R.M. van den Brink, MD, PhD

Memorial Sloan-Kettering Cancer Center

Jose Reyes, PhD
"Dynamics and consequences of complex karyotype evolution in p53 driven acute myeloid leukemia" with Scott Lowe, PhD, and Dana Pe'er, PhD

New York University School of Medicine

Robert S. Banh, PhD
"Metabolic contribution of sensory neurons to pancreatic tumorigenesis and serine metabolism, via peripheral axons" with Alec C. Kimmelman, MD, PhD, and Michael Pacold, MD, PhD
Shruti Naik, PhD
"Immune-epidermal stem cell crosstalk in skin inflammation"
Sophia Tintori, PhD
"Mechanisms of radiation tolerance in Caenorhabditis from Chernobyl" with Matthew Rockman, PhD
Rabi Upadhyay, MD
"Determining the distal effects of gut microbiota on the lung tumor microenvironment, cancer progression, and checkpoint blockade efficacy" with Dan R. Littman, MD, PhD

Stony Brook University

Benjamin L. Martin, PhD
"Cell cycle regulation of cellular behaviors associated with cancer metastasis"
David Q. Matus, PhD
"Cell cycle regulation of cellular behaviors associated with cancer metastasis"

The Rockefeller University

Aleksey Chudnovskiy, PhD
"Defining dendritic cell-T cell interaction history within the tumor microenvironment using enzymatic labeling" with Gabriel D. Victora, PhD
Gregory P. Donaldson, PhD
"Cross-talk between B lymphocytes and bacteria in the maintenance of a non-inflammatory mucosal microbiome" with Daniel Mucida, PhD
Yusong R. Guo, PhD
"Structural and mechanistic characterization of mechanosensitive Piezo channels" with Roderick MacKinnon, MD
Juhee Pae, PhD
"Mechanisms of germinal center B Cell proliferation" with Gabriel D. Victora, PhD
Yadira M. Soto-Feliciano, PhD
"Dissecting the role of Menin in acute leukemia" with C. David Allis, PhD
Linghe Xi, PhD
"WNT signaling and fate specification of normal versus tumorigenic stem cells" with Elaine Fuchs, PhD
John C. Zinder, PhD
"Structure and biochemistry of human shelterin and associated factors" with Titia de Lange, PhD

Weill Cornell Medicine

Christopher E. Barbieri, MD, PhD
"Subtype-specific modes of clinical and molecular progression in prostate cancer" with Lewis C. Cantley, PhD
John R. Ferrarone, MD
"Seeking and evaluating novel therapeutic targets in human lung adenocarcinomas with loss-of-function mutations in LKB1" with Harold E. Varmus, MD
Eric E. Gardner, PharmD, PhD
"Interrogating lung adenocarcinoma transformation to small cell lung cancer at single cell resolution" with Harold E. Varmus, MD
Jonathan E. Shoag, MD
"Harnessing clinical data to identify new prostate cancer therapeutics" with Christopher E. Barbieri, MD, PhD
Heather L. Yeo, MD
"Use of mobile applications to evaluate post surgical recovery in aging patients with GI cancer" with Manish A. Shah, MD, and Deborah L. Estrin, PhD

Duke University

Lawrence A. David, PhD
"Personalized prebiotics to optimize microbiota metabolism and improve transplant outcomes"
Nicholas C. DeVito, MD
"Investigating the role of EMT-mediated dendritic cell tolerization in checkpoint inhibitor resistance" with Brent A. Hanks, MD, PhD
Anthony D. Sung, MD
"Personalized prebiotics to optimize microbiota metabolism and improve transplant outcomes"

Oregon Health & Science University

Yunsik Kang, PhD
"Molecular mechanisms regulating phagocytosis of neurons" with Marc R. Freeman, PhD

Children's Hospital of Philadelphia

Jennifer M. Kalish, MD, PhD
"Epigenetic and genetic mechanisms of cancer in Beckwith-Wiedemann Syndrome" with Marisa S. Bartolomei, PhD, and Garrett A. Brodeur, MD

University of Pennsylvania, Philadelphia

Brian C. Capell, MD, PhD
"Defining the role of epigenetic enhancer dysfunction in epithelial carcinogenesis" with Shelley L. Berger, PhD
Geoffrey P. Dann, PhD
"Proteomics to bridge protein arginylation, chromatin, and cancer" with Benjamin A. Garcia, PhD
Romain L. Riscal, PhD
"Fructose 1,6 bisphosphatase nuclear localization, new function, and implication in Hepatocellular Carcinoma progression" with M. Celeste Simon, PhD

University of Pittsburgh

Abigail E. Overacre-Delgoffe, PhD
"Microbiome control of the tumor microenvironment: harnessing immunosuppression and exhaustion" with Timothy W. Hand, PhD, and Olivera Finn, PhD

University of Texas Southwestern Medical Center

Lindsay B. Case, PhD
"Regulation of integrin clustering on supported lipid bilayers" with Michael Rosen, PhD
Elise C. Jeffery, PhD
"Characterizing a new hematopoietic stem cell niche factor" with Sean Morrison, PhD
Xiaochun Li, PhD
“Investigations on Patched, a tumor suppressor, and its regulation in Hedgehog pathway”
David G. McFadden, MD, PhD
"Identifying metabolic vulnerabilities in Hürthle cell carcinoma" with Steven L. McKnight, PhD, and Ralph J. DeBerardinis, MD, PhD

University of Utah

Matthew P. Miller, PhD
"Deciphering tension-dependent stabilization of kinetochore-microtubule interactions"
Lexy von Diezmann, PhD
"State changes of a liquid-like compartment monitor crossover recombination" with Ofer Rog, PhD, and Erik Jorgensen, PhD

Washington University

Vivek K. Arora, MD, PhD
"Defining a targetable oncogenic dyad in bladder cancer" with Lee Ratner, MD, PhD
Gavin P. Dunn, MD, PhD
"Characterizing the immunogenic landscapes of malignant brain tumors" with John F. DiPersio, MD, PhD, and Robert D. Schreiber, PhD
Stephen T. Oh, MD, PhD
"Leveraging NFkB pathway dysregulation for therapeutic benefit in myeloproliferative neoplasms" with Daniel C. Link, MD
Darryl A. Wesener, PhD
"Synthetic food particles for studying human gut microbiota function" with Jeffrey I. Gordon, MD

The Ohio State University

Christin E. Burd, PhD
"Exploiting mutational specificity to target RAS-driven melanoma"
Wayne O. Miles, PhD
"Maximizing pro-apoptotic protein levels"

University of Wisconsin, Madison

Philip A. Romero, PhD
"Digital circulating tumor cell detection using scalable molecular logic"