Damon Runyon Researchers

Meet Our Scientists
Lindsay B. Case, PhD

Dr. Case is establishing an in vitro experimental system to study the formation of integrin signaling complexes on model membranes. Integrins form multiprotein signaling complexes that are essential for the survival, growth, and migration of tumor cells; integrins and their associated proteins are commonly mutated or misregulated in diverse cancer types. She will elucidate the molecular interactions and physical mechanisms that regulate the assembly of  integrin complexes to potentially reveal novel strategies for disrupting integrin signaling in cancer.

Project title: "Regulation of integrin clustering on supported lipid bilayers"
Institution: University of Texas Southwestern Medical Center
Named Award: Robert Black Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Michael Rosen, PhD
Cancer Type: All Cancers
Research Area: Biochemistry