Damon Runyon Researchers

Meet Our Scientists
Daniel H. Goldman, PhD

Dr. Goldman studies the process of protein synthesis, which is often misregulated in cancer, causing uncontrolled cell growth and proliferation. The balance of protein production in healthy cells is maintained in part by RNA-binding proteins, which modulate the efficiency of mRNA translation by the ribosome. However, the mechanisms underlying such regulation are not well understood. He is combining high-throughput sequencing technologies with single-molecule imaging in living cells to elucidate the mechanisms by which RNA-binding proteins regulate protein synthesis.

Project title: "Elucidating the role of the exon junction complex in regulating translation of spliced mRNA"
Institution: The Johns Hopkins University
Named Award: Merck Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Rachel Green, PhD
Cancer Type: All Cancers
Research Area: Biochemistry