Damon Runyon Researchers

Meet Our Scientists
Robert L. Bowman, PhD

Dr. Bowman focuses on acute myeloid leukemia (AML), which can be characterized by successive development of genetic mutations. While some mutations are found in nearly every cell of the disease, others are found in sub-populations and are thought to arise at later stages of disease development. It remains unclear if these late mutations are necessary for leukemic progression and are actionable therapeutic targets. He aims to develop models to test the oncogenic dependency of one of the most commonly mutated genes in AML, FLT3. Further models will be developed to understand the role of mutation order in disease development.

Project title: "Interrogating the subclonal architecture and functional contributions of mutation order in FLT3-ITD mutant AML"
Institution: Memorial Sloan Kettering Cancer Center
Award Program: Sohn Fellow
Cancer Type: Blood, Pediatric
Research Area: Animal Models/Mouse Models