Damon Runyon Researchers

Meet Our Scientists
Liron Bar-Peled, PhD

Dr. Bar-Peled studies how cancer cells adapt to stress environments, focusing on oxidative stress.  His research focuses on understanding how cells sense and respond to specific changes in their environment by activating singling pathways that lead to uncontrolled growth.  He recently studied a particular pathway in non-small cell lung cancer and identified a “druggable” protein that could be targeted with small molecules and disrupt this uncontrolled growth. He plans to pursue this specific target and use the same strategy for identifying druggable pathways in other cancers that currently lack effective therapies.

Project title: "Identification of cysteine liabilities in NRF2-driven cancers"
Institution: Massachusetts General Hospital
Award Program: Dale Frey Scientist
Cancer Type: All Cancers
Research Area: Chemical Biology