Damon Runyon Researchers

Dr. Singh is using cryo-electron tomography for structural investigations of the phase-separated transcriptional sites inside the cells. Faulty regulation of transcription from DNA to RNA is one of the major hallmarks of cancer. Dr. Singh aims to gain knowledge about the transcriptional sites to explain how different components come together to carry out transcription, their relationships with the rest of the cell, and what can go wrong in the process to cause disease.