Damon Runyon Researchers

Dr. Sulkowski [HHMI Fellow] investigates how solid tumors exist within dynamic microenvironments. Tumor cells hijack cell-to-cell communication mechanisms to interact with one another and their host to promote their growth. Dr. Sulkowski will study VHL deficient clear-cell renal cell carcinoma, the most common form of kidney cancer with more than 400,000 annual diagnoses worldwide. He will mechanistically investigate a novel phenomenon of active histone H3 secretion by cancer cells. By understanding the complex ways by which cancer cells interact with each other and their environment, this research could create new opportunities for cancer diagnosis and treatment.