Damon Runyon Researchers

Meet Our Scientists
Brooke D. Huisman, PhD

To prevent autoimmune attacks, T cells are screened in the thymus to ensure they do not react to self-derived antigens. Dr. Huisman studies the thymus and, specifically, a population of cells called “thymic mimetic cells” that mimic other tissues, such as muscle or gut, and assist T cells in developing tolerance to diverse cell types. Dr. Huisman’s research focuses on understanding how thymic mimetic cells develop. This work may lead to improved understanding of thymus-mediated tolerance to tumors, novel therapeutic opportunities for manipulating mimetic cells to induce anti-tumor responses, and increased understanding of thymic tumors. Dr. Huisman received her PhD from Massachusetts Institute of Technology, Cambridge and her BS from University of Michigan, Ann Arbor.

Project title: "Elucidating the lineage relationships of thymic mimetic cells"
Institution: Harvard Medical School
Award Program: Fellow
Sponsor(s) / Mentor(s): Diane Mathis, PhD, and Christophe Benoist, MD, PhD
Cancer Type: All Cancers
Research Area: Basic Immunology