Damon Runyon Researchers

Meet Our Scientists
Thomas M. Norman, PhD

Dr. Norman is investigating the role that “epigenetic” differences play in cancer cells’ ability to develop drug resistance. These epigenetic changes result in altered gene expression. He will use a new technique called CRISPRi to systematically tune the expression of different parts of the genome and measure their effect on drug resistance. He hopes that these studies will identify new avenues for reducing resistance and expand our knowledge of the role epigenetic factors play in leukemia and other cancers.

Project title: "Identifying the stochastic determinants of drug resistance"
Institution: University of California, San Francisco
Award Program: Fellow
Sponsor(s) / Mentor(s): Jonathan S. Weissman, PhD
Cancer Type: All Cancers
Research Area: Systems Biology