Damon Runyon Researchers

Meet Our Scientists
Duy P. Nguyen, PhD

Dr. Nguyen [Connie and Bob Lurie Fellow] is analyzing the bacterial enzyme Cas9, which has emerged to be a versatile tool to manipulate the genome. He aims to develop an efficient method for selective delivery to and activation of Cas9 in cancer cells. In addition, the proposed research will explore the possibility of genome manipulation to create genetic models for understanding the mechanistic role of programmed cell death. The developed methodology will hopefully set the foundation for rapidly creating genetic models to interrogate signaling pathways implicated in cancer and to investigate novel drug screening approaches that aim to identify new drug targets for cancer treatment.

Project title: "Genome editing via an engineered RNA-guided nuclease to create cancer genetic models"
Institution: University of California, San Francisco
Named Award: Connie and Bob Lurie Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): James A. Wells, PhD
Cancer Type: All Cancers
Research Area: Chemical Biology