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Antonio Cuevas-Navarro, PhD

Antonio Cuevas-Navarro, PhD

Project title
"Elucidating mechanisms that reverse the detrimental effect of RAS mutations in cancer"

Dr. Cuevas-Navarro’s [Berger Foundation Fellow] research project focuses on targeting mutations in the RAS genes (HRAS, NRAS, and KRAS), present in about 30% of cancer patients and notorious for driving aggressive tumor growth. Dr. Cuevas-Navarro aims to mitigate these mutations’ effects by using pharmacological agents to enhance a biochemical process that regulates RAS proteins. His project will investigate the mechanism of action of these compounds and assess their effectiveness in patient-derived cancer models. This research has the potential to expand treatment options across various cancer types, including those where current treatments are limited. Dr. Cuevas-Navarro received his PhD from University of California, San Francisco and his BS from University of California, Davis.

Institution
Memorial Sloan Kettering Cancer Center
Sponsor(s) / Mentor(s)
Piro Lito, MD, PhD
Cancer type
All Cancers
Research area
Biochemistry
Award Program
Fellow
Named Award
Berger Foundation Fellow