Devon Jeltema, PhD

A family of enzymes called PARPs help cells defend against viruses and other stressors by chemically modifying other molecules. While research on PARPs has historically focused on their modification of proteins, Dr. Jeltema’s research explores the modification of RNA by PARPs. Her project aims to investigate how RNA modification affects immune responses to threats like viral infection and cancer. Using biochemical and sequencing tools to map which RNA molecules are modified, Dr. Jeltema hopes to identify a new facet of immune defense that can be harnessed to treat cancer. Dr. Jeltema received her PhD from the University of Texas Southwestern Medical Center, Dallas, and her BS from Wheaton College, Norton.