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Ming M. Zheng, PhD

Ming M. Zheng, PhD

Project title
"Illuminate and Inhibit Cancer Progression at Single-Molecule Precision"

Many cancer treatments kill healthy cells along with cancer cells and tumors frequently adapt to treatment and build resistance. These challenges exist because the most important pathological cancer processes occur through complex interactions inside living cells, and the current models used to study cancer cannot fully mimic these complex living interactions. Dr. Zheng aims to combine large-scale genetic screening, advanced single-molecule imaging, and AI modeling to create detailed maps of how cancer-driving genes behave inside living human cells. These maps will show how networks of genes, as well as small DNA changes, alter the real-time behavior of powerful cancer drivers. This work will guide the development of treatments that cause less harm, stay effective longer, and act with far greater precision. Dr. Zheng received his PhD from Massachusetts Institute of Technology, Cambridge, and his BS from Peking University, Beijing.

Institution
The Broad Institute of MIT and Harvard
Sponsor(s) / Mentor(s)
Paul C. Blainey, PhD, and C. Sam Peng, PhD
Cancer type
All Cancers
Colorectal
Lung
Research area
Biophysics
Award Program
Fellow
Named Award
Robert Black Fellow