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Shuya Wang, PhD

Shuya Wang, PhD

Project title
"How chromosome instability causes epigenetic variation"

Even within the same tumor, cancer cells can differ in which genes they turn on or off, allowing some cells to adapt, survive treatment, or become more aggressive. These differences are often driven by changes in the epigenome, a layer of regulation that controls gene activity. Dr. Wang’s project explores the origin of epigenetic heterogeneity in cancer, focusing on the role of genome instability in driving epigenetic changes. By identifying the genes and pathways that connect these processes, she aims to better understand how cancer cells generate and maintain epigenetic heterogeneity, revealing new ways to limit tumor evolution, adaptation, and treatment resistance across all cancer types. Dr. Wang received her PhD from the University of California, Los Angeles, and her BS from Emory University, Decatur.

Institution
Dana-Farber Cancer Institute
Sponsor(s) / Mentor(s)
David S. Pellman, MD
Cancer type
All Cancers
Research area
Epigenetics
Award Program
Fellow
Named Award
Robertson Foundation Fellow