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Vivian Liu, MD

Vivian Liu, MD

Project title
Understanding mechanisms of transcriptional regulation and uncovering novel dependencies in NPM1-mutant AML

This project aims to better understand the biology of acute myeloid leukemia (AML), a blood cancer that affects white blood cells. The most common form of AML in adults involves a specific mutation in a gene known as NPM1. This mutation occurs in a consistent way and drives the growth of leukemia cells. Dr. Liu is investigating how this NPM1 mutation alters the behavior of leukemia cells and response to drug treatments, with the goal of developing new and more effective treatments for patients with this disease.

Institution
Fred Hutchinson Cancer Research Center
Sponsor(s) / Mentor(s)
Stanley C. Lee, PhD, and Soheil Meshinchi, MD, PhD
Cancer type
Blood
Research area
Cell Biology
Award Program
Physician-Scientist
Named Award
Leon and Toby Cooperman Physician-Scientist