Current and Former Awardees

Dale F. Frey Breakthrough Scientists

2018 Recipients

Ryan D. Baldridge, PhD
"Investigating the mechanism of retro-translocation by ERAD" at University of Michigan
Liron Bar-Peled, PhD
"Identification of cysteine liabilities in NRF2-driven cancers" at The Scripps Research Institute
Chao Lu, PhD
"Understanding the mechanism of histone H3 mutation in cancer initiation and maintenance" at Columbia University
Matthew P. Miller, PhD
"Regulation of kinetochore assembly" at Fred Hutchinson Cancer Research Center
Shruti Naik, PhD
"Immune-epidermal stem cell crosstalk in skin inflammation" at New York University School of Medicine
Neel H. Shah, PhD
"Interrogating ZAP-70 substrate recognition using high-throughput mutant screening" at University of California, Berkeley

2017 Recipients

Gira Bhabha, PhD
"High-resolution studies of dynein structure and mechanism" at New York University School of Medicine
Lydia Finley, PhD
"Metabolic regulation of cell fate decisions" at Memorial Sloan Kettering Cancer Center
Jens C. Schmidt, PhD
"Single molecule analysis of telomerase recruitment to telomeres" at University of Colorado
Jakob von Moltke, PhD
"Initiation of type 2 immune response" at University of Washington

2016 Recipients

Alistair N. Boettiger, PhD
"Using super-resolution imaging to probe molecular mechanisms of Polycomb silencing" at Stanford University
Mingye Feng, PhD
"Macrophage-mediated immunosurveillance in metastasis" at City of Hope
Ralph E. Kleiner, PhD
"Using chemistry to illuminate DNA and RNA damage processes in cells" at Princeton University

2015 Recipients

Angela N. Brooks, PhD
"Characterizing somatic mutations that affect mRNA splicing in cancer" at University of California, Santa Cruz
Sidi Chen, PhD
"Investigation of Dicer as a novel therapeutic route towards the inhibition of tumorigenesis and neoplastic growth" at Yale University
Robert K. McGinty, MD, PhD
"Structural studies of the MLL1 Core Methyltransferase complex" at Pennsylvania State University
Michael J. Smanski, PhD
"Establishing a versatile platform for functionalizing biological magnetic nanoparticles" at University of Minnesota
Angela J. Waanders, MD
"Preclinical models for therapeutic targeting of pediatric astrocytomas" at Children's Hospital of Philadelphia

2014 Recipients

David K. Breslow, PhD
Dissecting the role of the ciliary transport machinery in oncogenic signal transduction at Stanford University School of Medicine
Costas A. Lyssiotis, PhD
"Exploring the metabolic effects of oncogenic Kras in pancreatic ductual adenocarcinoma" at University of Michigan
Raymond E. Moellering, PhD
"Characterization of novel pathogenic pathways in cancer: do tumor cells use quorum-sensing molecules to support malignancy?" at The University of Chicago
Nathan D. Thomsen, PhD
“Molecular and cellular mechanism of caspase activation by small molecule pro-enzyme activators” at University of California, San Francisco
Cole Trapnell, PhD
“Globally characterizing lncRNA oncogenes with next-generation transciptomics” at University of Washington

2013 Recipients

Adam de la Zerda, PhD
“Molecular imaging of cell-cell signaling in the tumor microenvironment” at Stanford University
Gabriel C. Lander, PhD
“Structural basis of GTP hydrolysis in microtubule dynamic instability” at The Scripps Research Institute

2012 Recipients

Sean C. Bendall, PhD
"Improved single-cell phosphoprotein signaling analysis of oncogenic progression in leukemia" at Stanford University
Robert K. Bradley, PhD
“Investigating the splicing co-regulatory network” at Fred Hutchinson Cancer Research Center
Jason M. Crawford, PhD
“Systematic approaches to discovering bioactive bacterial metabolites” at Yale University

2011 Recipients

Ken Cadwell, PhD
“Characterization of mice deficient in autophagy protein Atg16L1” at New York University School of Medicine
L. Stirling Churchman, PhD
“Visualizing global transcription in vivo at nucleotide resolution” at Harvard Medical School
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