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By Joseph D. Mancias, MD, PhD, Damon Runyon Rachleff-Innovator at the Dana-Farber Cancer Institute
At the recent Accelerating Cancer Cures Symposium in New York City, I got an inside look at the cutting-edge cancer research presented by fellow Damon Runyon scientists. The unique symposium encourages networking with fellow awardees and pharmaceutical industry leaders.  Unlike solitary work in the lab, collaboration provides a synergy of ideas most likely to lead to unexpected paths of discovery.
The Damon Runyon Cancer Research Foundation (Damon Runyon) held the 8th annual Accelerating Cancer Cures Research Symposium. The annual meeting is designed to encourage collaboration between cancer researchers in industry and their counterparts in academia in order to overcome many of the issues that currently impede progress against cancer. Hosted this year by Lilly Oncology, the meeting included academic researchers from top universities and research institutions as well as scientists from Genentech, Gilead Sciences, Merck, Novartis, AbbVie and Amgen.
The success of CAR T (short for chimeric antigen receptor T) therapies, which essentially engineer a patient’s immune T cells to attack cancer cells, has been transformative in people with otherwise terminal blood cancers. However, many patients relapse, and CAR T therapy has not worked with solid tumors. Damon Runyon Clinical Investigator Christopher A. Klebanoff, MD, and colleagues at Memorial Sloan Kettering Cancer Center have discovered that the patient’s tumor may be sending a self-destruct signal, killing the CAR T cells. The researchers devised a way to cloak the cancer-fighting cells, so they survive to successfully attack the tumor.
Registration is now open for the 11th Annual Runyon 5K, which will be held on Saturday, May 11, 2019, at Yankee Stadium. 100% of donations raised will directly support bold and innovative scientists funded by the Damon Runyon Cancer Research Foundation.  Since the inaugural event in 2009, thousands of Runyon 5K participants have helped raise more than $5.2 million for breakthrough cancer research.
The Centers for Disease Control and Prevention (CDC) announced in August 2018 that, for the first time, the incidence of head and neck cancers caused by the human papillomavirus (HPV) surpassed that of cervical cancer in the United States.