Damon Runyon News

January 20, 2016

Piero D. Dalerba, MD (Damon Runyon-Rachleff Innovator ‘16-‘17), of Columbia University Medical Center, New York, and colleagues, have identified a biomarker, the CDX2 gene, that could be used to predict which stage II colon cancer patients may benefit from chemotherapy after surgery to prevent a recurrence of their disease. They found that cancers that do not express the gene have a worse prognosis than those that do. The study was published in the online edition of the New England Journal of Medicine.


January 6, 2016

David G. Kirsch, MD, PhD (Damon Runyon-Rachleff Innovator '08-'10, Innovation Award Committee Member) at the Duke University School of Medicine, Durham, and colleagues, have tested a new injectable agent that causes cancer cells in a tumor to fluoresce, potentially increasing a surgeon's ability to locate and remove all of a cancerous tumor on the first attempt.

January 6, 2016

Mark A. Lemmon, PhD (Damon Runyon Scholar ’97-‘98, Damon Runyon Fellow ’93-’96) of Yale University, New Haven, and colleagues at The Children's Hospital of Philadelphia reported that a next-generation ALK inhibitor drug, called PF-06463922, shows promise in treating pediatric neuroblastoma. In animal models, it caused rapid and sustained tumor regression and was more effective than the FDA-approved ALK inhibitor crizotinib.

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