Damon Runyon Researchers

Meet Our Scientists
Christopher J. Cambier, PhD

Dr. Cambier [HHMI Fellow] studies the role of cells called macrophages in mediating inflammation in immune responses to cancer. He is using the Mycobacterium marinum/zebrafish model of infection to examine misguided immune responses, many of which are shared with cancer. In particular, he proposes to study the distribution of a mycobacterial glycolipid molecule that is associated with driving macrophage activation and death, and will visualize the interactions of these glycolipids with macrophages in a living system. This new imaging approach along with the ability to manipulate host and pathogen genetics in a controlled setting will shed light on the inflammatory mechanisms driving disease. He hopes these findings will lead to new cancer therapies that modulate macrophages.

Project title: "In vivo characterization of mycobacterial cording"
Institution: Stanford University
Named Award: HHMI Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Carolyn Bertozzi, PhD
Cancer Type: All Cancers
Research Area: Infectious Disease